Family History Alone May Not Affect Breast Cancer Treatment Outcomes

Share this content:
A positive family history is not a significant independent risk factor for breast cancer outcome.
A positive family history is not a significant independent risk factor for breast cancer outcome.

A positive family history is not a significant independent risk factor for breast cancer outcome, according to a study published in the British Journal of Surgery.

The 2,850 women in the study were diagnosed from 2000 to 2008 and treated at 127 U.K. hospitals. Ramsey Cutress, B.M., B.Ch., Ph.D., an associate professor in breast surgery at the University of Southampton, and colleagues recorded tumor characteristics and asked each patient about family history. About one-third had at least one close relative with a history of breast or ovarian cancer.

RELATED: Tumor Infiltrating Lymphocytes Play Prognostic Role in Triple Negative Breast Cancer

The researchers found that there were no significant differences in distant disease-free intervals for patients with versus those without a family history, either for the entire cohort or when stratified by estrogen receptor status.

The findings should reassure young women "that their cancer should be treated in the usual way, and that the family history alone will not impact on their outcome," Cutress told HealthDay.

Reference

  1. Eccles, B. K., et al. "Family history and outcome of young patients with breast cancer in the UK (POSH study)." British Journal of Surgery. DOI: 10.1002/bjs.9816. [epub ahead of print]. May 20, 2015.

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs

Sign Up for Free e-newsletters