Oral Allergy Treatments: Rx

ORAL ALLERGY TREATMENTS: Rx
Generic Brand Strength Form Dose
ALLERGEN EXTRACT
short ragweed pollen allergen extract (Ambrosia artemisiifolia) Ragwitek 12 Amb a 1‑U sub-
lingual tabs
Children: <18yrs: not established.
Adults: See full labeling. Give 1st dose under physician supervision. ≥18−65yrs: 1 tab daily.
timothy grass pollen allergen extract Grastek 2800 BAUs sub-
lingual tabs
Adults and Children: <5yrs: not established. Initiate at least 12wks before onset of grass pollen season and continue throughout season. Give 1st dose under physician supervision; observe ≥30mins for signs/symptoms of a severe allergic reaction; if tolerated, subsequent doses may be taken at home. ≥5−65yrs: one tab daily.
ANTIHISTAMINE
(FIRST GENERATION H1 ANTAGONIST)
carbinoxamine maleate Arbinoxa 4mg scored tabs Children: <2yrs: Contraindicated. 2−5yrs: 0.2−0.4mg/kg/
day in 3−4 divided doses. 6−11yrs: 2−4mg 3−4 times daily.
Adults: 4−8mg orally 3−4 times daily.
4mg/
 
5mL
soln
cyprohepta-
dine HCl
4mg scored tabs Children: <2yrs: not recommended. 2−6yrs: 2mg 2−3 times per day; max 12mg daily. 7−14yrs: 4mg 2−3 times per day; max 16mg daily.
Adults: ≥14yrs: Initially 4mg 3 times daily; usual range 12−16mg/day; max 0.5mg/kg per day.
hydroxyzine HCl 10mg, 25mg, 50mg, 
100mg
tabs Children: <6yrs: 50mg daily. ≥6yrs: 50−100mg daily. Both in divided doses.
Adults: 25mg 3−4 times daily.
10mg/
 
5mL
syrup
hydroxyzine pamoate Vistaril 25mg, 50mg caps Children: <6yrs: 50mg daily. ≥6yrs: 50−100mg daily. Both in divided doses.
Adults: 25mg 3−4 times daily.
ANTIHISTAMINE
(SECOND GENERATION H1 ANTAGONIST)
desloratadine 2.5mg, 5mg ODT* Adults and Children: Dissolve on tongue; swallow with or without water. <6yrs: use other forms. 6−11yrs: 2.5mg once daily. ≥12yrs: 5mg once daily. Renal or hepatic impairment: Initially 5mg every other day.
Clarinex 5mg tabs Children: Use other forms.
Adults: 5mg once daily. Renal or hepatic impairment: Initially 5mg every other day.
0.5mg/
 
mL
syrup Adults and Children: <6mos: not recommended. 6−11mos: 1mg (2mL). 1−5yrs: 1.25mg (2.5mL). 6−11yrs: 2.5mg (5mL). ≥12yrs: 5mg (10mL). All: Once daily.
levocetirizine dihydro-
chloride
Xyzal 5mg scored tabs Children: <6mos: not recommended. 6mos−5yrs: max 1.25mg once daily in the PM. 6−11yrs: max 2.5mg once daily in the PM. Renal dysfunction: Contraindicated.
Adults: 2.5mg−5mg once daily in the PM. Renal dysfunction: CrCl 50−80mL/min: 2.5mg once daily; CrCl 30−50mL/min: 2.5mg every other day; CrCl 10−30mL/min: 2.5mg twice per week (every 3−4 days); CrCl <10mL/min or hemodialysis: Contraindicated.
0.5mg/
 
mL
soln
LEUKOTRIENE RECEPTOR ANTAGONIST
montelukast (as sodium) Singulair 10mg tabs Adults and Children: Take granules by mouth within 15min of opening packet; may dissolve in 5mL of cold or room temperature baby formula or breast milk, or mix in spoonful of soft applesauce, carrots, rice, or ice cream. <6mos w/perennial allergic rhinitis or <2yrs w/seasonal allergic rhinitis: not established. 6−23mos: one 4mg granule packet. 2−5yrs: One 4mg chew tab or granule packet. 6−14yrs: One 5mg chew tab. ≥15yrs: One 10mg tab. For all: Take once daily.
4mg, 5mg chew tabs*
4mg/
 
packet
oral gran-
ules
MAST CELL STABILIZER
cromolyn sodium Gastrocrom 100mg/
 
5mL
oral concen-
trate
Adults and Children: Mix contents of amp in water and drink. Take dose 4 times daily at regular intervals, 30min before meals and at bedtime; may increase if insufficient response within 2−3 weeks. <2yrs: Usually not recommended; see literature. 2−12yrs: 100mg. ≥13yrs: 200mg. All: max 40mg/kg per day; maintain at lowest effective dose.
ANTIHISTAMINE + SYMPATHOMIMETIC
acrivastine/
pseudoephe-
drine HCl
Semprex-D 8mg/
 
60mg
caps Children: Not recommended.
Adults: 1 cap every 4−6hrs, max 4/day.
desloratadine/
pseudoephe-
drine sulfate
Clarinex-D 12 Hour 2.5mg/
 
120mg
ext-rel tabs Children: Not recommended.
Adults: Swallow whole. 1 tab twice daily.
Clarinex-D 24 Hour 5mg/
 
240mg
ext-rel tabs Children: Not recommended.
Adults: Swallow whole. 1 tab once daily.
NOTES

Key: ODT = orally disintegrating tablets; soln = solution;  * = contains phenylalanine; † = contains alcohol.

Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 7/2015)

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