Everolimus is a promising treatment option for pancreatic neuroendocrine tumors (pNETs), even though dose reductions are required for most patients.
Intraoperatively-placed 5-fluouracil (5-FU) chemotherapy at lymph node surgical dissection beds may lower the chance of necessary surgery.
Pancreatic neuroendocrine tumors (pNETs) harbor genetic mutations in DNA repair pathways that represent "strong candidates".
CHICAGO, IL—Durable, complete tumor regression can occur following a single infusion of human papillomavirus tumor-infiltrating lymphocytes in women with metastatic cervical cancer.
CHICAGO, IL—Ibrutinib significantly improved progression-free survival, overall survival, and overall response rate when compared with ofatumumab in patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma.
CHICAGO, IL—Established biomarkers failed to predict response to platinum in patients with metastatic triple-negative breast cancer.
CHICAGO, IL— Discontinuation of statin therapy does not shorten survival and improves quality of life among patients with a life expectancy of less than 1 year.
CHICAGO, IL— Non-small cell lung cancer tumors that progress on the epidermal growth factor receptor tyrosine kinase inhibitors erlotinib/gefitinib and afatinib continue to depend on ErbB family receptor signaling.
LY2157299 monohydrate showed promising efficacy results in patients with advanced HCC tumors overexpressing AFP.
Circulating tumor cells are a useful adjunct in the diagnosis of pancreatic ductal adenocarcinoma.
PET/CT may prevent unnecessary laparotomy by detecting occult metastatic disease in patients with resectable/borderline pancreatic cancer.
Nab-paclitaxel plus gemcitabine sustained overall survival rates compared with gemcitabine alone in patients with metastatic pancreatic adenocarcinoma.
Cetuximab should not be added to first-line FOLFOX4 for patients whose mCRC harbors RAS mutations.
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