Conference Coverage

Complete Conference Coverage

Durvalumab Does Not Worsen Quality of Life Among Patients With Unresectable NSCLC

Durvalumab Does Not Worsen Quality of Life Among Patients With Unresectable NSCLC

During a plenary presentation at the 18th annual WCLC, researchers presented patient-reported outcomes, including health-related QoL, disease symptoms, and physical function, from the phase 3 PACIFIC trial.

Nivolumab Plus Chemotherapy Improves Overall Survival and Response Rate in NSCLC

Nivolumab Plus Chemotherapy Improves Overall Survival and Response Rate in NSCLC

Researchers randomly assigned 56 treatment-naive patients with advanced NSCLC to 3 cohorts: nivolumab plus gemcitabine and cisplatin, nivolumab plus pemetrexed and cisplatin, and nivolumab plus paclitaxel and carboplatin.

Smoking Tobacco Increases Costs and Decreases QoL in Advanced NSCLC

Smoking Tobacco Increases Costs and Decreases QoL in Advanced NSCLC

For this cross-sectional study, researchers collected the data of 1030 adult patients with advanced NSCLC from medical chart reviews and various patient questionnaires.

Post-surgery Chemotherapy Based on BRCA1 Levels Fails To Improve Survival in NSCLC

Post-surgery Chemotherapy Based on BRCA1 Levels Fails To Improve Survival in NSCLC

One-hundred and eight patients received cisplatin plus docetaxel in the control arm; 392 patients in the experimental arm received varying treatments according to BRCA1 mRNA expression levels.

NSCLC: Researchers Identify Socioeconomic Factors Linked to Overall Survival

NSCLC: Researchers Identify Socioeconomic Factors Linked to Overall Survival

Researchers evaluated survival and socioeconomic data from 1,150,722 patients with NSCLC to determine particular factors that may predict OS.

Savolitinib Plus Gefitinib May Be Effective in EGFR-Mutant, MET-amplified NSCLC

Savolitinib Plus Gefitinib May Be Effective in EGFR-Mutant, MET-amplified NSCLC

Researchers administered savolitinib 600 mg plus gefitinib 250 mg to 44 patients, of whom 6 were T790M-positive and 5 were T790M-negative.

Maintenance Pazopanib Provides PFS, not OS, Benefit in Small-cell Lung Cancer

Maintenance Pazopanib Provides PFS, not OS, Benefit in Small-cell Lung Cancer

Investigators randomly assigned 95 patients with ED-SCLC to receive pazopanib 800 mg daily or placebo.

Pembrolizumab Plus Pemetrexed, Carboplatin Prolongs Survival in NSCLC

Pembrolizumab Plus Pemetrexed, Carboplatin Prolongs Survival in NSCLC

Initial analysis of cohort G of KEYNOTE-021 at a median of 10.6 months showed that pembrolizumab significantly improved overall response rate and progression-free survival compared with pemetrexed/carboplatin alone.

Repeat T790M Testing Recommended for TKI-resistant Patients With NSCLC

Repeat T790M Testing Recommended for TKI-resistant Patients With NSCLC

Researchers analyzed the resistance biopsies and plasma specimens of 119 patients with T790M-positive NSCLC treated with osimertinib.

Anetumab Ravtansine Does Not Improve PFS vs Vinorelbine in Second-line Mesothelioma

Anetumab Ravtansine Does Not Improve PFS vs Vinorelbine in Second-line Mesothelioma

Researchers enrolled 248 patients who progressed on pemetrexed-based chemotherapy with or without bevacizumab to receive second-line anetumab ravtansine or vinorelbine.

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