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Treating advanced melanoma: Current insights and opportunities

Treating advanced melanoma: Current insights and opportunities

[Cancer Management and Research] Although thin melanomas have an excellent prognosis after sufficient surgical treatment, melanoma disease in advanced stages still proves to be a therapeutic challenge. In the last several years, new therapeutic strategies have emerged.

Human Papilloma Virus and Squamous Cell Carcinoma of the Anus

Human Papilloma Virus and Squamous Cell Carcinoma of the Anus

[Clin Med Insights Oncol] HPV is a risk factor for anal intraepithelial neoplasia (AIN). The etiology, anatomy, pathogenesis, management of squamous cell carcinoma (SCC) are discussed.

New Combination Therapies May Improve Survival Rates for Patients with Melanoma

New Combination Therapies May Improve Survival Rates for Patients with Melanoma

Research from the ESMO 2014 Congress suggest that combination therapies may improve the rate of survival for patients with melanoma.

Clinical Trials and Tribulations in Oncology

Clinical Trials and Tribulations in Oncology

Over the past decade, there has been significant progress in the development of novel cancer therapies.

Current Approaches and Emerging Directions in HER2-resistant Breast Cancer

Current Approaches and Emerging Directions in HER2-resistant Breast Cancer

[Breast Cancer (Auckl)] Human epidermal growth factor receptor-2 is overexpressed in up to 30% of breast cancers; indicative of poor prognosis.

PD-1 Pathway Inhibitors: Changing the Landscape of Cancer Immunotherapy

PD-1 Pathway Inhibitors: Changing the Landscape of Cancer Immunotherapy

[Cancer Control] Immunotherapeutic approaches to treating cancer have been evaluated during the last few decades with limited success.

Primary Androgen-Deprivation Therapy (ADT) for Localized Prostate Cancer: Potential for Harm May Outweigh Benefit in Low-Risk Disease

Primary Androgen-Deprivation Therapy (ADT) for Localized Prostate Cancer: Potential for Harm May Outweigh Benefit in Low-Risk Disease

Although ADT remains an important treatment, its use as primary therapy in low-risk prostate cancer seems increasingly ill advised.

Biomarkers of HIV-associated Cancer

Biomarkers of HIV-associated Cancer

[Biomark Cancer] Biomarkers can provide great opportunities in the management of the most common HIV-associated malignancies, namely, Kaposi sarcoma, non-Hodgkin's lymphoma, and invasive cervical cancer.

Oral Contraceptives and the Risk of Breast Cancer

Oral Contraceptives and the Risk of Breast Cancer

Certain oral contraceptives may increase breast cancer risk, but researchers caution that the risk is small, if it exists at all.

FDG-PET/CT in the Assessment of Treatment Response after Oncologic Treatment of Head and Neck Squamous Cell Carcinoma

FDG-PET/CT in the Assessment of Treatment Response after Oncologic Treatment of Head and Neck Squamous Cell Carcinoma

[Clin Med Insights Ear Nose Throat] 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is used to monitor treatment response after definitive (chemo)radiotherapy for head and neck squamous cell carcinoma, but its usefulness remains controversial.

New Therapies in T-cell Lymphoma

New Therapies in T-cell Lymphoma

[Lymphoma and Chronic Lymphocytic Leukemias] Biomarker-driven chemotherapeutics is becoming a critical part of the state-of-the-art treatment in early- and late-phase clinical trials involving patients with T-cell lymphoma.

Diarrhea and Patients With Cancer

Diarrhea and Patients With Cancer

Diarrhea is a treatment symptom as common as hair loss but with deadlier implications.

Cervical Cancer Rates May Be Higher in Older Women Than Previously Reported

Cervical Cancer Rates May Be Higher in Older Women Than Previously Reported

Rate of cervical cancer in African-American women is higher than what was previously recognized.

AMEN Protocol Designed to Help Clinicians When Patients Hope for Miracles

AMEN Protocol Designed to Help Clinicians When Patients Hope for Miracles

The protocol was developed to guide clinicians who have limited medical intervention options.

No Silver Bullet for Patient Nonadherence to Oral Anticancer Therapies

No Silver Bullet for Patient Nonadherence to Oral Anticancer Therapies

Oncologists need more information on the factors that lead to nonadherence in order to actively prevent it.

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