Almost Half of Colorectal Cancer Survivors Experience Continued Pain

Share this content:
Almost half of CRC survivors with pain interference during the initial phase of care have continued PI post-treatment.
Almost half of CRC survivors with pain interference during the initial phase of care have continued PI post-treatment.

Almost half of colorectal cancer (CRC) survivors with pain interference (PI) during the initial phase of care have continued PI post-treatment, according to a study published in Pain Medicine.

Kelly Kenzik, Ph.D., from the University of Alabama at Birmingham, and colleagues analyzed survey results from CRC participants of the Cancer Care Outcomes Research and Surveillance Consortium during the initial phase of care (baseline to under one year; 2,961 patients) and follow-up (about one year post-diagnosis; 2,303 patients).

The researchers found that at baseline and follow-up, 24.7 and 23.7 percent of participants reported moderate and high PI, respectively. PI was equivalent or increasing at follow-up among 46 percent of those with baseline PI. 

Female gender, comorbidities, depression, chemotherapy, and radiation were associated with moderate/high PI, both near diagnosis and at follow-up, while older age was protective of PI. Equivalent or increasing PI was associated with pulmonary disease and heart failure comorbidities.

RELATED: Women Overweight in Youth May Face Higher Colorectal Cancer Risk

There was also a significant association between PI and no longer having a job at follow-up among survivors who were employed at baseline.

"PI may be related to continuing normal activities, that is, work, after completed treatment," the authors write.

Reference

  1. Kenzik, Kelly, PhD, et al. "Unresolved Pain Interference among Colorectal Cancer Survivors: Implications for Patient Care and Outcomes." Pain Medicine. DOI: 10.1111/pme.12727. [epub ahead of print]. March 20, 2015.

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs

Sign Up for Free e-newsletters