General Oncology

Massage and Cancer

Massage and Cancer

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On overview of the research regarding the use of massage to improve cancer- or treatment-related symptoms and overall quality of life for patients with cancer.

Reprogramming T Cells Without Using Viral Vectors

Reprogramming T Cells Without Using Viral Vectors

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According to recent research, scientists may not need to rely on the use of viral vectors to edit the genes of primary immune cells when creating cell and gene therapies.

Is Genomic Medicine Failing Minority Patients?

Is Genomic Medicine Failing Minority Patients?

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Racial minorities are poorly represented in genomic research databases, raising important questions about whether or not all patients will benefit equally from advances in precision oncology.

Progress Report in Cancer Control: How Are We Doing?

Progress Report in Cancer Control: How Are We Doing?

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An analysis of population data on cancer incidence, survival, and mortality revealed that early interventions and improvements to treatments contributed to a 26% decline in cancer deaths from 1991 to 2015.

Sildenafil and Cancer: The Potential Positives

Sildenafil and Cancer: The Potential Positives

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Examining the costs and benefits of repurposing sildenafil as a cancer medication.

FDA's Accelerated Approval Pathway Needs Active Management

FDA's Accelerated Approval Pathway Needs Active Management

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Results from postmarketing trials for drugs approved through FDA's accelerated approval pathway need to be produced in a more timely fashion to reveal the true benefit — or lack thereof — of the drugs approved through these expedited channels.

Mobile Phones and Cancer

Mobile Phones and Cancer

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Multiple studies have examined the possible association between cell phone usage and increased cancer risk, but study designs, potential biases, and interpretations of statistical outcomes leave conclusions uncertain.

Q&A With Frank Luh, MD, MS, MHA and Yun Yen, MD, PhD, FACP: Looking to Broaden CMS Coverage for NGS Tests

Q&A With Frank Luh, MD, MS, MHA and Yun Yen, MD, PhD, FACP: Looking to Broaden CMS Coverage for NGS Tests

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Restricting use to FDA-approved NGS tests is not an absolute rule that must last forever. But it's a good start, say two physicians.

Young Adult, Adolescent Survivors of Cancer May Have Increased Long-Term Risk for Endocrine Disease

Young Adult, Adolescent Survivors of Cancer May Have Increased Long-Term Risk for Endocrine Disease

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There is a paucity of data regarding the long-term endocrine effects of cancer in adolescent and young adult survivors.

Exercise Therapy May Improve Cardiorespiratory Fitness in Adult-Onset Cancer

Exercise Therapy May Improve Cardiorespiratory Fitness in Adult-Onset Cancer

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Exercise therapy may improve peak oxygen consumption and improve clinical outcomes, but findings from previous studies have been inconclusive.

Indoor Tanning and Cancer

Indoor Tanning and Cancer

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All meta-analyses conducted to date show a significant association between indoor tanning use and an increased risk of melanoma or non-melanoma skin cancers.

Medicare Reimbursement Restrictions on Next-Generation Sequencing Could Hinder Clinical Decision-Making

Medicare Reimbursement Restrictions on Next-Generation Sequencing Could Hinder Clinical Decision-Making

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Requiring FDA approval for next-generation sequencing assays may restrict scientific development and strangle innovation.

Assumptions about Survival for Patients With Cancer Should Not Influence ICU Admission Decisions

Assumptions about Survival for Patients With Cancer Should Not Influence ICU Admission Decisions

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In the short term, patients in the ICU with solid malignancies had favorable survival outcomes compared to all other ICU patients — and even in the long term, when adjusting for prognostic factors, ICU patients with cancer did not represent meaningful increases in hospital mortality risk.

Survey-based priming intervention linked to improved communication and goals-of-care discussions amongst patient-clinician pairs

Communication remains one of the cornerstone principles in the foundation of medical practice.

Do the Risks of Direct-to-Consumer Testing Outweigh the Benefits?

Do the Risks of Direct-to-Consumer Testing Outweigh the Benefits?

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There are benefits and drawbacks to the public availability to DTC mutation tests.

Resveratrol and Cancer

Resveratrol and Cancer

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Though mechanisms of anticancer effects of resveratrol have been identified, the ability to translate these findings to in-human studies is a challenge.

<i>ARID1A</i> Mutations Might Predict Tumor Response to Immunotherapy

ARID1A Mutations Might Predict Tumor Response to Immunotherapy

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New findings bolster the case for the predictive utility of ARID1A mutations.

High Tissue Tumor Mutational Burden May Be Predictive of Improved Immunotherapy Efficacy

High Tissue Tumor Mutational Burden May Be Predictive of Improved Immunotherapy Efficacy

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Data from previous studies evaluating the efficacy of atezolizumab, a PD-L1 inhibitor, have suggested that high tissue tumor mutational burden may be predictive of efficacy for checkpoint immunotherapy.

Liquid Biopsies and Cancer Detection: New Test Assesses Levels of Circulating Proteins for Early-Stage Diagnosis

Liquid Biopsies and Cancer Detection: New Test Assesses Levels of Circulating Proteins for Early-Stage Diagnosis

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A new test has been shown to be capable of identifying eight different cancers by assessing levels of circulating proteins along with mutations in cell-free DNA.

Vigorous Exercise Improved Life Expectancy for Adult Survivors of Childhood Cancers

Vigorous Exercise Improved Life Expectancy for Adult Survivors of Childhood Cancers

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Researchers report on a retrospective cohort analysis that evaluated the long-term effects of vigorous exercise for survivors of childhood cancer.

Understanding Telomerase: Higher Quality Images Give Insight Into Developing New Agents for Inhibition

Understanding Telomerase: Higher Quality Images Give Insight Into Developing New Agents for Inhibition

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Telomerase plays a crucial role in tumor proliferation, and a better understanding of its structure will pave the way for new drug development.

Coffee and Cancer

Coffee and Cancer

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Several meta-analyses suggest that coffee consumption may decrease the risk of many types of cancers, but for some cancers, the data remain mixed or indicate an increased risk.

Risk of Diabetes May Increase After Cancer Diagnosis

Risk of Diabetes May Increase After Cancer Diagnosis

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Many studies have suggested that diabetes is a risk factor for the development of cancer, but whether or not cancer itself can increase the risk of diabetes requires further investigation.

Efficacy and Hyperemesis Syndrome Associated With Cannabinoid Use in Cancers ― In the Clinic

Efficacy and Hyperemesis Syndrome Associated With Cannabinoid Use in Cancers ― In the Clinic

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Many clinical trials and systematic reviews note that the use of cannabinoids also comes with adverse events, including a clinical entity that has been gaining evidence in the literature over the last decade called cannabinoid hyperemesis syndrome.

Achieving Long-Term Viral Suppression May Reduce Risk of AIDS-Related Cancers

Achieving Long-Term Viral Suppression May Reduce Risk of AIDS-Related Cancers

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Researchers hypothesized that ART, which suppresses viral load, improves immune function, and reduces inflammation, may lead to reduced cancer risk among HIV-positive patients.

IBM Watson Health Data Presented at ASCO 2018

IBM Watson Health Data Presented at ASCO 2018

Kyu Rhee, MD, MPP, discusses the latest updates at the ASCO 2018 meeting.

Latest Innovations in Value-Based Specialty Care

Latest Innovations in Value-Based Specialty Care

Charles Saunders, MD, speaks at the American Society of Clinical Oncology (ASCO) 2018 meeting in Chicago.

Investigational Studies on Lenvatinib, Pembrolizumab

Investigational Studies on Lenvatinib, Pembrolizumab

Josh Kremer, MD, discusses the latest research at the ASCO 2018 meeting.

Innovations in Engaging T-cells

Innovations in Engaging T-cells

Venkateshwar Reddy, MD, discusses research at the ASCO 2018 meeting.

President's Address at ASCO 2018 Emphasizes Growth, Delivery, Reach of Precision Medicine

President's Address at ASCO 2018 Emphasizes Growth, Delivery, Reach of Precision Medicine

With precision medicine nearly 23% of all patients who present with advanced lung cancer are treated with FDA- or EMA-approved targeted therapies or immunotherapies instead of chemotherapy.

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