Sonography, MRI Comparable for Cervical Cancer Staging

Share this content:
Transvaginal sonography is comparable to magnetic resonance imaging (MRI) for diagnosing and staging local cervical cancer.
Transvaginal sonography is comparable to magnetic resonance imaging (MRI) for diagnosing and staging local cervical cancer.

Transvaginal sonography (TVS), performed by a dedicated gynecologic radiologist, is comparable to magnetic resonance imaging (MRI) for diagnosing and staging local cervical cancer, according to a study published in the Journal of Clinical Ultrasound.

Fiachra Moloney, M.D., from Cork University Hospital in Ireland, and colleagues compared the diagnostic accuracy of TVS with MRI for the local staging of cervical cancer in 46 patients diagnosed with invasive carcinoma of the cervix over a three-year period.

The researchers observed a strong correlation between MRI and TVS in the assessment of tumor volume in both early-stage and advanced-stage disease (P < 0.0001). Both technologies had a sensitivity of 80 percent, a specificity of 50 percent, and a diagnostic accuracy of 63.6 percent for the detection of stromal invasion in early-stage disease.

Sensitivity, specificity, and diagnostic accuracy rates varied for MRI and TVS detection of parametrial invasion: sensitivity of 40 and 86 percent, respectively; specificity of 78.8 and 20 percent, respectively; and diagnostic accuracy of 89 and 78.7 percent, respectively.

RELATED: Cervical Cancer Survival Influenced by Presence of Diabetes Mellitus

However, in a matched-sample analysis there was no statistically significant difference between MRI and TVS in the assessment of stromal or parametrial invasion (P = 0.06).

"TVS performed by a dedicated gynecologic radiologist is a feasible and economic imaging modality with a diagnostic accuracy comparable to that of MRI," the authors write.

"It may be used as an adjunct to MRI for the local staging of invasive cervical cancer or to allow for rapid and confident triage of patients into operative and nonoperative categories for management in the gynecologic outpatient setting."

Reference

  1. Moloney F, Ryan D, Twomey M, et al. Comparison of MRI and high-resolution transvaginal sonography for the local staging of cervical cancer. Journal of Clinical Ultrasound. [online ahead of print]. 2015. DOI: 10.1002/jcu.22288.

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs

Sign Up for Free e-newsletters