Researchers continue to search for a molecular pathway or biomarker to improve treatment options for patients with sorafenib-refractory HCC.
CASI Pharmaceuticals announced that the FDA has granted Orphan Drug designation to ENMD-2076 for the treatment of hepatocellular carcinoma.
Researchers found no survival difference found between patients receiving everolimus or placebo.
The benefits of hepatocellular carcinoma screening are unclear in patients with chronic liver disease.
A new study in Western Europeans shows that vitamin D lowers the risk of developing hepatocellular carcinoma.
Researchers have found that antiviral therapy may be successful in preventing hepatitis B virus from developing into the most common form of liver cancer, hepatocellular carcinoma.
Measurement of α-fetoprotein detects hepatocellular carcinoma most accurately in patients without hepatitis C virus infection.
Celsion announced updated results from its HEAT Study post-hoc analysis which examined the use of ThermoDox, a heat-activated liposomal encapsulation of doxorubicin, in combination with radiofrequency ablation (RFA) for the treatment of hepatocellular carcinoma (HCC).
The FDA has approved Guerbet's Lipiodol (ethiozed oil) injection for imaging of hepatocellular carcinoma tumors
Increased coffee consumption may reduce hepatocellular carcinoma risk across ethnicities, according to a study presented at the AACR Annual Meeting.
LY2157299 monohydrate showed promising efficacy results in patients with advanced HCC tumors overexpressing AFP.
Data indicate that everolimus did not improve overall survival in patients with advanced HCC following sorafenib failure.
Sorafenib can be an effective treatment for a variety of cancers, but its use can come with significant GI side effects.
Immunotherapy targeting the CLTA4 protein in HCV-related HCC demonstrated modest extended survival in a disease that has a high mortality rate.
Despite HCC having a poor prognosis and high mortality, systemic antiangiogenesis therapies offer some hope to patients.
Forming a multidisciplinary clinic for patients with HCC resulted in improved survival, likely due to more streamlined care and earlier diagnosis, found research presented at SSO 2013.
Radiofrequency ablation might offer comparable survival rates when compared with liver surgery for patients with hepatocellular carcinoma.
Aspirin use, but not the use of other nonsteroidal anti-inflammatory drugs (NSAIDs), is associated with a reduced risk of developing hepatocellular carcinoma.
Patients with advanced unresectable hepatocellular carcinoma have a higher median overall survival when treated with drug eluting bead transarterial chemoembolization.
Drug-eluting beads are a new type of drug delivery system that may be able to decrease side effects and localize chemotherapy treatment in HCC patients.
The first patient has been treated in a phase 2 clinical trial of intravenous delivery JX-594 in patients with advanced hepatocellular carcinoma.
In a randomized phase 3 trial, first-line brivanib did not meet its primary overall survival end point in patients with hapatocellular carcinoma.
A cohort study of Danish patients with alcoholic cirrhosis suggests that because they are at low risk for hepatocellular carcinoma (HCC), "surveillance would be expected to have a minimal effect on mortality and is unlikely to be cost effective,"
The investigators sought to understand the relationships between familial clustering of hepatocellular carcinoma (HCC), family history of liver cancer and the incidence of hepatitis.
Danish researchers have established a link between childhood obesity and hepatocellular carcinoma (HCC) in adults.
Loco-regional therapy with selective internal radiation therapy (SIRT) and sorafenib demonstrated good efficacy in patients with advanced hepatocellular carcinoma (HCC), especially those in Barcelona Clinic Liver Criteria (BCLC) stage B.
The search for a drug that can treat many different forms of cancer may be over. This comes with news that Isis Pharmaceuticals has initiated a Phase 1 study targeting the expression in tumors of signal transducer and activator of transcription 3 (STAT3), a gene that is ubiquitous and overexpressed in many tumor types.
Transarterial chemoembolization (TACE) with sequential sorafenib delayed time to progression (TTP) of intermediate-stage hepatocellular carcinoma (HCC) in patients with chronic hepatitis C virus (HCV) infection, a prospective randomized study concluded in The Oncologist online February 14.
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