Higher ERDP scores were significantly associated with developing breast cancer.
Immunotherapy may supplant sunitinib in RCC, except for in patients who cannot tolerate checkpoint inhibition.
Preventive treatments are strongly recommended in women with AH and LCIS.
Patients with CLL may have both disease-associated and systemic treatment-associated immune dysfunction, leaving them vulnerable to infection.
Many HIV-associated cancers develop with the help of oncoviruses — some of which are sexually transmitted.
Postapproval studies are needed to further characterize the risk and long-term safety of immune checkpoint inhibition.
Knowing that food increases the absorption of some therapies presents the possibility of easily — and significantly — lowering treatment costs.
Preclinical models indicated that dual inhibition of BTK and BCL2 may be synergistic.
Brentuximab vedotin is an anti-CD30 monoclonal antibody that targets the Reed-Sternberg cells found in patients with classical HL.
It is unclear whether breast cancer screening — and specifically mammography — reduces the likelihood of being diagnosed with advanced-stage disease.
Results from the Prostate Cancer Prevention Trial indicate that the reduced risk for prostate cancer among men assigned to finasteride continued throughout 16 years of follow-up.
Most tumors do not respond, or evolve resistance, to immune checkpoint inhibition. Now, researchers at Johns Hopkins have engineered a new class of cancer immunotherapy agents designed to short-circuit key mechanisms of tumors' disruption and evasion of immune system attack.
Phase 1 trials should be considered therapeutic options for some patients.
The risk should not discourage patients with cancer from taking these potentially life-extending therapies.
One study's results may be especially relevant for patients eligible for treatment discontinuation.
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