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Lung Cancer Comprehensive Smoke-free Ordinances Reduce Risk of Lung Cancer

Comprehensive Smoke-free Ordinances Reduce Risk of Lung Cancer

People living in counties with strong smoke-free policies were 7.9% less likely to be diagnosed with lung cancer compared with those living in counties with no protection.

General Oncology Can Inhibiting Ubiquitin Target Undruggable Tumor Proteins?

Can Inhibiting Ubiquitin Target Undruggable Tumor Proteins?

A class of DUBs known as the ubiquitin-specific-processing proteases are involved in regulating the p53 signaling pathway and have been implicated in tumorigenesis and radiotherapy resistance.

Breast Cancer Metastatic Breast Cancer: What To Look For

Metastatic Breast Cancer: What To Look For

As breast cancer can be asymptomatic or have a series of different symptoms and physical exam findings, standard procedure is hard to define.

General Oncology The Warburg Effect: Can Cancer Be Starved of Sugar?

The Warburg Effect: Can Cancer Be Starved of Sugar?

A recent study into the relationship between glucose and cancer cell proliferation may be helping to identify a therapeutic route to starve tumors without killing normal cells.

Skin Cancer Monitoring for Post-organ Transplant Skin Cancer: Patients and Physicians Both Play A Vital Role

Monitoring for Post-organ Transplant Skin Cancer: Patients and Physicians Both Play A Vital Role

As post-transplant medications are used to reduce the body's immune reaction to a foreign organ, they may also reduce the body's ability to accurately survey for malignant cells.

Multiple Myeloma Q&A With Shaji Kumar, MD: Looking to the Future of Multiple Myeloma Treatment

Q&A With Shaji Kumar, MD: Looking to the Future of Multiple Myeloma Treatment

Cancer Therapy Advisor asked Shaji Kumar, MD, to share his thoughts about where we are now and where we are going regarding promising data and novel approaches for MM treatment.

Lymphoma Toward An Understanding of Molecular DLBCL Subtypes

Toward An Understanding of Molecular DLBCL Subtypes

Continued, deliberate exploration of the molecular pathways involved in different subsets of the disease is crucial to achieve clinical advances in the future.

Renal Cell Carcinoma Smoking After Diagnosis Leads to Worse Renal Cell Carcinoma-specific Survival

Smoking After Diagnosis Leads to Worse Renal Cell Carcinoma-specific Survival

Cigarettes may favor VHL-intact RCC, but it is unclear whether cigarette smoking selects for more aggressive histology of RCC in a similar way to, for example, the TP53 mutation in lung cancer.

General Oncology Rare Cancer: An Underserved Area of Oncology

Rare Cancer: An Underserved Area of Oncology

As more rare cancers are identified, the need for rethinking approaches to research will become greater.

Renal Cell Carcinoma Overexpression of CKAP4 Linked With Poor Prognosis in Renal Cell Carcinoma

Overexpression of CKAP4 Linked With Poor Prognosis in Renal Cell Carcinoma

Overexpressed CKAP4 was significantly associated with tumor, nodal, and metastasis stages, as well as Fuhrman grades.

Prostate Cancer Does Education Level Predict PSA Screening and Prostate Cancer Survival?

Does Education Level Predict PSA Screening and Prostate Cancer Survival?

Socioeconomic status, including education and income level, appears to be tied to prostate-specific antigen test results and prostate cancer treatment and survival, but the exact nature of these associations is not yet clear.

Chronic Myeloid Leukemia Do Additional Chromosomal Abnormalities Noted at CML Diagnosis Affect Response and Survival?

Do Additional Chromosomal Abnormalities Noted at CML Diagnosis Affect Response and Survival?

Although cytogenetic abnormalities that arise during the course of CML are prevalent in later stages of the disease and are associated with a poorer prognosis, as many as 10% to 12% of patients exhibit ACAs at diagnosis.

Breast Cancer Can Targeting Inflammatory Microenvironments Improve Cancer Therapy Effectiveness?

Can Targeting Inflammatory Microenvironments Improve Cancer Therapy Effectiveness?

Targeting tumor and extracellular LPA could help deny tumors their inflammatory habitat and improve the efficacy of radiotherapy, chemotherapy, and possibly immunotherapies.

Skin Cancer The Challenges of Immunotherapy Re-challenge in Metastatic Melanoma

The Challenges of Immunotherapy Re-challenge in Metastatic Melanoma

It is not always clear whether patients who discontinue anti-PD-1 and -CTLA-4 therapy should re-initiate treatment after adverse events are resolved.

Lung Cancer Beta-blockers May Prevent Stress-induced Lung Cancer Treatment Resistance

Beta-blockers May Prevent Stress-induced Lung Cancer Treatment Resistance

The results of this study support previous findings that psychological distress is associated with an increased risk of mortality among patients with lung cancer.

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