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Prostate Cancer Lower Cabazitaxel Dose May Benefit Patients With Prostate Cancer

Lower Cabazitaxel Dose May Benefit Patients With Prostate Cancer

The lesser toxicity of the 20 mg/m2 dose compared with the 25 mg/m2 dose may benefit frail patients in particular, or those with poor functional status.

Lung Cancer ThromboSeq and Tumor-educated Platelets for Lung Cancer Detection

ThromboSeq and Tumor-educated Platelets for Lung Cancer Detection

The thromboSeq test result might not only provide information regarding lung cancer diagnostics, but potentially any other tumor types as well, and may enable tumor-type stratification.

Lymphoma Treatment Considerations for Older Patients With Lymphoma

Treatment Considerations for Older Patients With Lymphoma

As patients become older, additional factors must be considered in planning their treatment.

Multiple Myeloma Paths Forward for Confronting Extramedullary Multiple Myeloma

Paths Forward for Confronting Extramedullary Multiple Myeloma

Extramedullary multiple myeloma is increasingly encountered in the clinic and most patients will need aggressive treatment.

Breast Cancer CDK4/6 Inhibitors in Breast Cancer Treatment: Recent Research, Safety Profiles, Acquired Resistance, Next Steps

CDK4/6 Inhibitors in Breast Cancer Treatment: Recent Research, Safety Profiles, Acquired Resistance, Next Steps

Breast tumors can become resistant to CDK 4/6 inhibitors, but improved understanding of the mechanisms of acquired resistance might point to additional treatment strategies.

Head and Neck Cancer Volatile Organic Compounds and Esophageal Cancer: Understanding the Implications for Diagnosis and Treatment

Volatile Organic Compounds and Esophageal Cancer: Understanding the Implications for Diagnosis and Treatment

While utilization of VOCs in the early detection of esophageal cancer has shown promise, future studies should aim at determining which VOCs would be the most specific in diagnosing GI malignancies.

Chronic Myeloid Leukemia Understanding Blast Phase Chronic Myeloid Leukemia

Understanding Blast Phase Chronic Myeloid Leukemia

A new study finds some hopeful signs of progress in understanding blast phase CML, which is typically associated with poor outcomes.

Renal Cell Carcinoma Multigene Test May Help Identify Hereditary Kidney Cancers

Multigene Test May Help Identify Hereditary Kidney Cancers

Hereditary kidney cancer syndromes are often diagnosed by astute clinicians who recognize that there is more to a patient's diagnosis then just the random event of getting cancer.

Lung Cancer Tumor Re-Biopsy May Be Best Option to Identify Cause of EGFR-TKI Resistance in NSCLC

Tumor Re-Biopsy May Be Best Option to Identify Cause of EGFR-TKI Resistance in NSCLC

Not conducting a second tissue biopsy could have dangerous implications for the patient according to a recent article.

Multiple Myeloma Virotherapy for Multiple Myeloma: The Current State of Research

Virotherapy for Multiple Myeloma: The Current State of Research

An emerging approach in the early stages of clinical development for MM is oncolytic virotherapy, in which viruses are used to eliminate cancer cells directly or indirectly.

Breast Cancer Q&A With Dr Chao: Oncotype DX Breast Recurrence Score® and Breast DCIS Score™

Q&A With Dr Chao: Oncotype DX Breast Recurrence Score® and Breast DCIS Score™

CTA spoke with Calvin Chao, MD, about how the Oncotype DX® test is implemented, how results can guide treatment, its use globally, and the future of prognostic testing.

Lung Cancer An Uncertain Future for Durvalumab in Lung Cancer Management

An Uncertain Future for Durvalumab in Lung Cancer Management

Durvalumab's optimal clinical role in managing lung cancer remains unclear and more robust predictive biomarkers are needed.

Renal Cell Carcinoma Sirolimus Use in Graft Versus Host Disease

Sirolimus Use in Graft Versus Host Disease

As more experience with sirolimus has been gained, it began to be used "off-label" to prevent rejection in multiple transplant recipients and is now being studied in the treatment of GVHD.

Skin Cancer Knowledge of Immunotherapies in Melanoma Continues to Grow

Knowledge of Immunotherapies in Melanoma Continues to Grow

Clinicians continue to learn about which patients will benefit most from different immunotherapy treatments, and how dosing can effect adverse events.

Renal Cell Carcinoma Telomere Length May Predict Renal Cell Carcinoma Risk in Patients with VHL

Telomere Length May Predict Renal Cell Carcinoma Risk in Patients with VHL

There are estimated to be 13 distinct hereditary renal cell carcinoma (RCC) syndromes, each of which is associated with specific germline mutations, including von Hippel-Lindau disease (VHL).

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