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Gastrointestinal Cancers Immunotherapy of Advanced Colorectal Cancer By Enlisting Bystander T Cells

Immunotherapy of Advanced Colorectal Cancer By Enlisting Bystander T Cells

Study results presented at ASCO point to a major advance for immune therapy in advanced CEA-expressing CRC and possibly other CEA-expressing malignancies.

Lymphoma In Focus: Blinatumomab for Non-Hodgkin Lymphoma

In Focus: Blinatumomab for Non-Hodgkin Lymphoma

Although blinatumomab shows promising antitumor activity among patients with varying subtypes of NHL, the incidence of neurologic toxicity is high.

Chronic Myeloid Leukemia TKI Discontinuation for Patients With CML Could Save Billions

TKI Discontinuation for Patients With CML Could Save Billions

With the average uninsured cost of TKI treatment close to or above $146,000 per year per patient with CML in the United States, reducing or ending treatment would yield billions in savings.

General Oncology Supreme Court Ruling Should Hasten Arrival of Biosimilars, But Uncertainties Remain

Supreme Court Ruling Should Hasten Arrival of Biosimilars, But Uncertainties Remain

The Supreme Court's ruling in the Amgen v Sandoz case may hasten the arrival of lower-cost biosimilar versions of biologics in the clinic, potentially saving billions of dollars in health care spending.

Breast Cancer Q&A With Filippo Montemurro, MD: Considerations for Treatment With Trastuzumab Emtansine

Q&A With Filippo Montemurro, MD: Considerations for Treatment With Trastuzumab Emtansine

Cancer Therapy Advisor asked Filippo Montemurro, MD, to place recent findings in context with respect to when T-DM1 might be best indicated.

Multiple Myeloma Vaccines Targeting Multiple Myeloma Offer Promising Therapeutic Approach

Vaccines Targeting Multiple Myeloma Offer Promising Therapeutic Approach

Vaccines targeting multiple myeloma antigens offer a promising therapeutic approach by helping the immune system to fight off cancer cells.

Breast Cancer In Focus: Abemaciclib for Advanced Breast Cancer

In Focus: Abemaciclib for Advanced Breast Cancer

Several presentations demonstrated that abemaciclib provides clinical benefit for women with HR+/HER2-negative breast cancer who progress on or are resistant to endocrine therapy.

Sarcoma Future Treatment Modalities in Sarcoma: Insights From ASCO 2017

Future Treatment Modalities in Sarcoma: Insights From ASCO 2017

Targeted and immunotherapeutic approaches are poised to change how sarcoma will be treated in the future. Trials are being used to match tumors with appropriate treatment choices.

Breast Cancer Overcoming Drug Resistance in the Treatment of Metastatic Breast Cancer

Overcoming Drug Resistance in the Treatment of Metastatic Breast Cancer

The management of metastatic breast cancer resistant or refractory to hormonal treatments, while still challenging, is rapidly improving.

Sarcoma Aldoxorubicin: A Way Forward for Soft Tissue Sarcoma?

Aldoxorubicin: A Way Forward for Soft Tissue Sarcoma?

Although aldoxorubicin did not improve OS, the available evidence suggests that it is nevertheless superior to doxorubicin — particularly among patients with liposarcoma and leiomyosarcoma.

General Oncology Engagement Is Survival: My Take on ASCO 2017

Engagement Is Survival: My Take on ASCO 2017

Don Dizon, MD: In addition to important clinical trial outcomes that evaluated novel strategies across tumor types, there were impressive studies aiming to help our patients live with cancer as well.

Breast Cancer Q&A With Narjust Duma, MD: Minority Patient Participation in Breast Cancer Clinical Trials

Q&A With Narjust Duma, MD: Minority Patient Participation in Breast Cancer Clinical Trials

In this question-and-answer session, Cancer Therapy Advisor asked Dr Duma about her team's study and minority patient representation in breast cancer studies.

Breast Cancer Cryosurgery: The Future of Breast Cancer Treatment?

Cryosurgery: The Future of Breast Cancer Treatment?

Whether cryosurgery or cryoablation will prove a viable alternative to lumpectomy — the standard of care for women with early breast cancer — remains uncertain.

Renal Cell Carcinoma Advanced Renal Cell Carcinoma: Interviews With Neeraj Agarwal, MD, and Ulka Vaishampayan, MD

Advanced Renal Cell Carcinoma: Interviews With Neeraj Agarwal, MD, and Ulka Vaishampayan, MD

Ulka Vaishampayan, MD, and Neeraj Agarwal, MD, spoke with Cancer Therapy Advisor about treatment recommendations for patients newly diagnosed with metastatic RCC.

Gastrointestinal Cancers Gastric Linitis Plastica Diagnosis Uses Endoscopic and Radiologic Studies Approach

Gastric Linitis Plastica Diagnosis Uses Endoscopic and Radiologic Studies Approach

The diagnosis of linitis plastica, a subtype of gastric adenocarcinoma with a poor prognosis, can be difficult and uses a multifaceted approach between endoscopic and radiologic studies.

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