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Elderly Patients with Rectal Cancer May Face Similar Survival Outcomes as Younger Patients

Elderly Patients with Rectal Cancer May Face Similar Survival Outcomes as Younger Patients

Older patients seem to face similar outcomes as younger patients when treated with neoadjuvant chemoradiation for rectal cancer.

HPV16 DNA Rinse Post Treatment Could Predict Recurrence

HPV16 DNA Rinse Post Treatment Could Predict Recurrence

Human papillomavirus (HPV) type 16 DNA in oral rinses is common at diagnosis, but rare after treatment for HPV oropharyngeal carcinoma (OPC).

Germline HABP2 Mutation Associated with Familial Nonmedullary Thyroid Cancer

Germline HABP2 Mutation Associated with Familial Nonmedullary Thyroid Cancer

HABP2 G534E variant is a susceptibility gene for familial nonmedullary thyroid cancer and functions as a dominant-negative tumor-suppressor gene.

Adding Vosaroxin to Cytarabine May Benefit Some with Acute Myeloid Leukemia

Adding Vosaroxin to Cytarabine May Benefit Some with Acute Myeloid Leukemia

Addition of vosaroxin to cytarabine might be of clinical benefit to some patients with relapsed or refractory acute myeloid leukemia (AML).

Incidence Rates of Anal Carcinoma, Adenocarcinoma Have Increased Significantly

Incidence Rates of Anal Carcinoma, Adenocarcinoma Have Increased Significantly

Incidence rates (IRs) of anal squamous cell carcinoma (SCC) and squamous carcinoma in situ (CIS) have significantly increased overtime.

Tyrosine Kinase Inhibitors May Be Safe For Chronic Myeloid Leukemia

Tyrosine Kinase Inhibitors May Be Safe For Chronic Myeloid Leukemia

Tyrosine kinase inhibitors (TKIs) may be a safe treatment option for patients with chronic-phase (CP) chronic myeloid leukemia (CML) .

Symptoms in Pediatric Cancer Do Not Coincide with Proxy Reports

Symptoms in Pediatric Cancer Do Not Coincide with Proxy Reports

Symptoms are common among children diagnosed with cancer; however, children's reports of these symptoms do not match proxy reports.

In Early-Stage Breast Cancer, Regional Nodal Irradiation May Reduce Recurrence

In Early-Stage Breast Cancer, Regional Nodal Irradiation May Reduce Recurrence

Among women with early-stage breast cancer, addition of regional nodal irradiation to whole-breast irradiation reduced the rate of breast cancer recurrence.

Modified FCR Regimen No More Effective for Previously Untreated Chronic Leukemia

Modified FCR Regimen No More Effective for Previously Untreated Chronic Leukemia

In previously untreated chronic lymphocytic leukemia (CLL), modified fludarabine, cyclophosphamide, and rituximab (FCR) resulted in similar outcomes.

Possible Link Between Pembrolizumab Cutaneous Adverse Reaction, Progression-Free Survival

Possible Link Between Pembrolizumab Cutaneous Adverse Reaction, Progression-Free Survival

Cutaneous adverse events while receiving pembrolizumab has been linked with better treatment response, especially in melanoma.

Telomere Length May Help Predict Risk of Lung Cancer

Telomere Length May Help Predict Risk of Lung Cancer

Individuals with long telomeres are at increased risk for lung adenocarcinoma but not other types of cancer.

Superior Survival Associated with Treatment at NCI-designated Cancer Centers

Superior Survival Associated with Treatment at NCI-designated Cancer Centers

Patients with adult-onset cancer who were treated at National Cancer Institute-designated comprehensive cancer centers demonstrated greater survival.

U.S. Medical Groups Combating Prescription Opioid Abuse

U.S. Medical Groups Combating Prescription Opioid Abuse

A group of 27 major U.S. medical organizations are banding together to tackle the continuing epidemic of opioid abuse.

Methods of Analyzing Pathways of Colorectal Cancer in Middle East May Be Ineffective

Methods of Analyzing Pathways of Colorectal Cancer in Middle East May Be Ineffective

A majority of Middle Eastern colorectal cancer (CRC) cases was designated as part of the unassigned group.

Primary Melanoma Treatment Outcome Factors Identified

Primary Melanoma Treatment Outcome Factors Identified

Sex, LDH level, BRAF genotype, and ulceration status identified as being independent factors associated with treatment outcomes in melanoma.

Diagnostic Model Developed for Impending Death in Patients with Cancer

Diagnostic Model Developed for Impending Death in Patients with Cancer

A diagnostic model for impending death within 3 days was developed for patients with cancer.

Modified 2/1 Sunitinib Schedule May Be Safer in Renal Cell Carcinoma

Modified 2/1 Sunitinib Schedule May Be Safer in Renal Cell Carcinoma

Patients with metastatic renal cell carcinoma who transitioned to a modified 2/1 schedule of sunitinib experience an improved safety profile.

Febuxostat Superior to Allopurinol for Prevention of Tumor Lysis Syndrome

Febuxostat Superior to Allopurinol for Prevention of Tumor Lysis Syndrome

Febuxostat achieved a significant serum uric acid control in patients with hematologic malignancies at tumor lysis syndrome risk.

Comparison of Two S-1 Plus Cisplatin Dosing Schedules Shows No Survival Advantage

Comparison of Two S-1 Plus Cisplatin Dosing Schedules Shows No Survival Advantage

No difference in overall survival and either can be used as first-line treatments for patients with advanced gastric cancer.

Racial Differences Persist in Cause-specific Mortality in Breast Cancer

Racial Differences Persist in Cause-specific Mortality in Breast Cancer

While breast cancer-specific mortality among older women has improved across all races in recent years, other cause-mortality has not.

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