In Primary Cutaneous Melanoma, Tumor Cell Adhesion Increases Risk for Sentinel Lymph Node Metastasis
The addition of cell adhesion-linked gene expression variables to clinicopathologic variables improves the identification of patients with SLN metastases within 90 days of thin or intermediate-thickness melanoma diagnosis.
Concurrent chemoradiotherapy alone should remain the standard of care for the treatment of patients with locally advanced NSCLC.
Confirmed molecular subtypes in leiomyosarcoma are linked to distinct clinical outcomes.
Patients with stage 4 colorectal cancer who have the variant rs9929218 at 16q22 are at an increased risk for worse survival and poor response to chemotherapy.
The assessment of metabolic response and EGFR using FDG-PET may assist physicians in predicting the likelihood of achieving pathological complete response.
Single-nucleotide polymorphisms and genetically determined race were identified as two significant biomarkers associated with predicting taxane-induced peripheral neuropathy in patients.
Lower average relative dose intensity linked to worse overall and ovarian cancer-specific survival
A significant relationship has been found between coffee consumption and a reduced risk of developing HCC, but not with IHC.
Women with longer amounts of leisure-time spent sitting have a greater risk of total cancer, while no correlation was found between sitting time and men
High-dose chemoradiotherapy and watchful waiting might be a safe alternative to abdominoperineal resection for the treatment of patients with distal rectal cancer.
Final results from the OPTIMAL trial showed that patients with mutant type EGFR showed significant OS benefit when treated with EGFR and TKI erlotinib.
Use of statins may improve lung surgery results, but a larger controlled study is needed to further investigate potential benefits.
Ibrutinib combined with ofatumumab is well-tolerated and active in patients with relapsed chronic lymphocytic leukemia (CLL).
Preceding myeloproliferative neoplasm is a predictor for poor outlook in patients who develop new primary cancers.
Minimal residual disease MRD measured by flow cytometry is highly prognostic in pediatric B-precursor ALL.
A retrospective analysis showed that first-line bevacizumab treatment may provide overall survival in glioblastoma.
Partner-assisted skin self-examination interventions were efficacious for early detection of individuals with history of melanoma.
In patients with myelofibrosis treated with ruxolitinib, harboring three or more mutations was inversely associated with response.
Robotic surgery is safe and feasible for the surgical management of morbidly obese patients with endometrial cancer.
Citrus consumption has been linked to increased risk of malignant melanoma in two cohorts of women and men.
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Cancer Therapy Advisor Articles
- Ipilimumab Can Be Infused Safely Over 30 Minutes
- Older Adults with Head and Neck Cancers May Need More Cautious Treatment Strategies
- Link Between Citrus Consumption and Melanoma
- Filgrastim Biosimilar Appears Equally Safe, Effective for Breast Cancer
- Bevacizumab with Chemo Improves Survival in Ovarian Cancer with Poor Prognosis
- In Primary Cutaneous Melanoma, Tumor Cell Adhesion Increases Risk for Sentinel Lymph Node Metastasis
- Concurrent Chemoradiotherapy Should Remain Standard of Care for Locally Advanced NSCLC
- Clinically Relevant Molecular Subtypes in Leiomyosarcoma
- Variant rs9929218 Linked with Prognosis of Patients with CRC
- FDG-PET in Predicting Response Rates in Triple-Negative Breast Cancer
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