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Dexrazoxane Not Associated with Late Mortality in Pediatric Patients

Dexrazoxane Not Associated with Late Mortality in Pediatric Patients

Dexrazoxane treatment did not seem to compromise overall survival among pediatric patients with leukemia or lymphoma.

First-Line Bevacizumab for Glioblastoma Not Likely To Be Cost-Effective

First-Line Bevacizumab for Glioblastoma Not Likely To Be Cost-Effective

Bevacizumab has limited effectiveness and is therefore not likely to be cost effective in newly diagnosed glioblastoma multiforme.

Nivolumab Appears Safe, Effective in Wild-Type, Mutant BRAF Melanoma

Nivolumab Appears Safe, Effective in Wild-Type, Mutant BRAF Melanoma

Nivolumab has similar efficacy and safety outcomes in patients with wild-type or mutant BRAF metastatic melanoma.

Primary Androgen Deprivation Raises Diabetes Risk by 60 Percent

Primary Androgen Deprivation Raises Diabetes Risk by 60 Percent

Primary androgen deprivation therapy increases diabetes risk, particularly in men under 70 years of age.

Population-Based Fecal Testing May Reduce Colorectal Cancer Mortality

Population-Based Fecal Testing May Reduce Colorectal Cancer Mortality

Population-based fecal immunochemical testing (FIT) screening in adults aged 50 to 69 years can reduce colorectal cancer (CRC) mortality.

Mediterranean Diet May Lower Risk of Endometrial Cancer

Mediterranean Diet May Lower Risk of Endometrial Cancer

Adhering to a Mediterranean diet may significantly reduce a woman's risk of endometrial cancer.

Adding Radiotherapy to ADT Only Slightly Impacts Quality of Life in Prostate Cancer

Adding Radiotherapy to ADT Only Slightly Impacts Quality of Life in Prostate Cancer

When radiotherapy was added to androgen deprivation therapy, only minimal impact on health-related quality-of-life in prostate cancer

Adding Bevacizumab Has No Impact on Quality of Life in Glioblastoma

Adding Bevacizumab Has No Impact on Quality of Life in Glioblastoma

Adding bevacizumab to standard treatment of glioblastoma may have no impact on health-related quality of life.

First Oncolytic Immunotherapy Improves Durable Response Rate in Melanoma

First Oncolytic Immunotherapy Improves Durable Response Rate in Melanoma

Talimogene laherparepvec (T-VEC) is the first oncolytic immunotherapy to demonstrate therapeutic benefit against melanoma.

Adding Bevacizumab Effective in Chinese Patients with Nonsquamous Lung Cancer

Adding Bevacizumab Effective in Chinese Patients with Nonsquamous Lung Cancer

Addition of bevacizumab to carboplatin/paclitaxel well tolerated in Chinese patients with nonsquamous non-small cell lung cancer (NSCLC).

Many Patients with Cancer Showing Interest in Genetic Profiling

Many Patients with Cancer Showing Interest in Genetic Profiling

Many patients with cancer are interested in comprehensive tumor genetic profiling (CGP), and most are willing to pay out-of-pocket costs for CGP.

Vismodegib Safe, Effective in Twelve-Month Study Update

Vismodegib Safe, Effective in Twelve-Month Study Update

Vismodegib is safe and effective in the management of advanced basal cell carcinoma (BCC).

Dovitinib Shows Activity in Advanced Endometrial Cancer

Dovitinib Shows Activity in Advanced Endometrial Cancer

Second-line dovitinib in FGFR2-mutated and FGFR2-non-mutated advanced or metastatic endometrial cancer had single-agent activity.

Chromosomal Instability Associated with Improved Outcomes in Breast Cancer

Chromosomal Instability Associated with Improved Outcomes in Breast Cancer

Association between extreme chromosomal instability and improved outcome in estrogen receptor (ER)-negative breast cancers.

Colonoscopies Underperformed for Younger, High-Risk Americans

Colonoscopies Underperformed for Younger, High-Risk Americans

A majority of people with a family history of colorectal cancer (CRC) are not getting screened for the disease early enough.

Azacitadine May Be Safe, Effective for Older Patients with Acute Myeloid Leukemia

Azacitadine May Be Safe, Effective for Older Patients with Acute Myeloid Leukemia

Azacitadine may be an important treatment option for older patients with newly diagnosed acute myeloid leukemia (AML).

Addition of Levetiracetam May Improve Survival for Glioblastoma

Addition of Levetiracetam May Improve Survival for Glioblastoma

Levetiracetam may provide a survival benefit in patients with glioblastoma who receive temozolomide-based chemotherapy.

Gender Disparity in Receipt of End-of-Life Care

Gender Disparity in Receipt of End-of-Life Care

There are gender differences in receipt of end-of-life (EoL) care among terminally ill cancer patients.

Family History Alone May Not Affect Breast Cancer Treatment Outcomes

Family History Alone May Not Affect Breast Cancer Treatment Outcomes

A positive family history is not a significant independent risk factor for breast cancer outcome.

Surgery Before Chemotherapy Beneficial in Advanced Ovarian Cancer

Surgery Before Chemotherapy Beneficial in Advanced Ovarian Cancer

Undergoing chemotherapy before surgery may help women battling advanced ovarian cancer.

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