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In Primary Cutaneous Melanoma, Tumor Cell Adhesion Increases Risk for Sentinel Lymph Node Metastasis

In Primary Cutaneous Melanoma, Tumor Cell Adhesion Increases Risk for Sentinel Lymph Node Metastasis

The addition of cell adhesion-linked gene expression variables to clinicopathologic variables improves the identification of patients with SLN metastases within 90 days of thin or intermediate-thickness melanoma diagnosis.

Concurrent Chemoradiotherapy Should Remain Standard of Care for Locally Advanced NSCLC

Concurrent Chemoradiotherapy Should Remain Standard of Care for Locally Advanced NSCLC

Concurrent chemoradiotherapy alone should remain the standard of care for the treatment of patients with locally advanced NSCLC.

Clinically Relevant Molecular Subtypes in Leiomyosarcoma

Clinically Relevant Molecular Subtypes in Leiomyosarcoma

Confirmed molecular subtypes in leiomyosarcoma are linked to distinct clinical outcomes.

Variant rs9929218 Linked with Prognosis of Patients with CRC

Variant rs9929218 Linked with Prognosis of Patients with CRC

Patients with stage 4 colorectal cancer who have the variant rs9929218 at 16q22 are at an increased risk for worse survival and poor response to chemotherapy.

FDG-PET in Predicting Response Rates in Triple-Negative Breast Cancer

FDG-PET in Predicting Response Rates in Triple-Negative Breast Cancer

The assessment of metabolic response and EGFR using FDG-PET may assist physicians in predicting the likelihood of achieving pathological complete response.

Predictors for Pts at Risk for Developing Taxane-Induced Peripheral Neuropathy

Predictors for Pts at Risk for Developing Taxane-Induced Peripheral Neuropathy

Single-nucleotide polymorphisms and genetically determined race were identified as two significant biomarkers associated with predicting taxane-induced peripheral neuropathy in patients.

Reduced Chemotherapy Doses Linked to Decreased Survival in Ovarian Cancer

Reduced Chemotherapy Doses Linked to Decreased Survival in Ovarian Cancer

Lower average relative dose intensity linked to worse overall and ovarian cancer-specific survival

Coffee Consumption Associated with Lower Risk of Hepatocellular Carcinoma in a US Population

Coffee Consumption Associated with Lower Risk of Hepatocellular Carcinoma in a US Population

A significant relationship has been found between coffee consumption and a reduced risk of developing HCC, but not with IHC.

Leisure Sitting Time Linked to Increased Risk of Developing Malignancies in Women

Leisure Sitting Time Linked to Increased Risk of Developing Malignancies in Women

Women with longer amounts of leisure-time spent sitting have a greater risk of total cancer, while no correlation was found between sitting time and men

High-Dose CRT Plus Watchful Waiting May Be Safe Alternative for Distal Rectal Cancer

High-Dose CRT Plus Watchful Waiting May Be Safe Alternative for Distal Rectal Cancer

High-dose chemoradiotherapy and watchful waiting might be a safe alternative to abdominoperineal resection for the treatment of patients with distal rectal cancer.

Final OS Results from the Phase 3 OPTIMAL Trial in EGFR-Positive NSCLC

Final OS Results from the Phase 3 OPTIMAL Trial in EGFR-Positive NSCLC

Final results from the OPTIMAL trial showed that patients with mutant type EGFR showed significant OS benefit when treated with EGFR and TKI erlotinib.

Statin Use Tied to Better Post-Surgical Outcomes

Statin Use Tied to Better Post-Surgical Outcomes

Use of statins may improve lung surgery results, but a larger controlled study is needed to further investigate potential benefits.

Ibrutinib Plus Ofatumumab Tolerable, Active for Relapsed CLL

Ibrutinib Plus Ofatumumab Tolerable, Active for Relapsed CLL

Ibrutinib combined with ofatumumab is well-tolerated and active in patients with relapsed chronic lymphocytic leukemia (CLL).

Prior Myeloproliferative Neoplasm Associated with Poor Outlook in Patients with New Primary Cancers

Prior Myeloproliferative Neoplasm Associated with Poor Outlook in Patients with New Primary Cancers

Preceding myeloproliferative neoplasm is a predictor for poor outlook in patients who develop new primary cancers.

Prognostic Significance of Minimal Residual Disease in Pediatric B-ALL

Prognostic Significance of Minimal Residual Disease in Pediatric B-ALL

Minimal residual disease MRD measured by flow cytometry is highly prognostic in pediatric B-precursor ALL.

Bevacizumab May Add Survival Benefit for Wild-type Proneural Glioblastoma

Bevacizumab May Add Survival Benefit for Wild-type Proneural Glioblastoma

A retrospective analysis showed that first-line bevacizumab treatment may provide overall survival in glioblastoma.

Partner-Assisted Skin Self-Exams Beneficial for Patients with Melanoma

Partner-Assisted Skin Self-Exams Beneficial for Patients with Melanoma

Partner-assisted skin self-examination interventions were efficacious for early detection of individuals with history of melanoma.

In Myelofibrosis, Ruxolitinib Response Associated with Mutation Profile

In Myelofibrosis, Ruxolitinib Response Associated with Mutation Profile

In patients with myelofibrosis treated with ruxolitinib, harboring three or more mutations was inversely associated with response.

Robotic Surgery Viable for Obese Women with Endometrial Cancer

Robotic Surgery Viable for Obese Women with Endometrial Cancer

Robotic surgery is safe and feasible for the surgical management of morbidly obese patients with endometrial cancer.

Link Between Citrus Consumption and Melanoma

Link Between Citrus Consumption and Melanoma

Citrus consumption has been linked to increased risk of malignant melanoma in two cohorts of women and men.

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