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In Early-Stage Breast Cancer, Regional Nodal Irradiation May Reduce Recurrence

In Early-Stage Breast Cancer, Regional Nodal Irradiation May Reduce Recurrence

Among women with early-stage breast cancer, addition of regional nodal irradiation to whole-breast irradiation reduced the rate of breast cancer recurrence.

Modified FCR Regimen No More Effective for Previously Untreated Chronic Leukemia

Modified FCR Regimen No More Effective for Previously Untreated Chronic Leukemia

In previously untreated chronic lymphocytic leukemia (CLL), modified fludarabine, cyclophosphamide, and rituximab (FCR) resulted in similar outcomes.

Possible Link Between Pembrolizumab Cutaneous Adverse Reaction, Progression-Free Survival

Possible Link Between Pembrolizumab Cutaneous Adverse Reaction, Progression-Free Survival

Cutaneous adverse events while receiving pembrolizumab has been linked with better treatment response, especially in melanoma.

Telomere Length May Help Predict Risk of Lung Cancer

Telomere Length May Help Predict Risk of Lung Cancer

Individuals with long telomeres are at increased risk for lung adenocarcinoma but not other types of cancer.

Superior Survival Associated with Treatment at NCI-designated Cancer Centers

Superior Survival Associated with Treatment at NCI-designated Cancer Centers

Patients with adult-onset cancer who were treated at National Cancer Institute-designated comprehensive cancer centers demonstrated greater survival.

U.S. Medical Groups Combating Prescription Opioid Abuse

U.S. Medical Groups Combating Prescription Opioid Abuse

A group of 27 major U.S. medical organizations are banding together to tackle the continuing epidemic of opioid abuse.

Methods of Analyzing Pathways of Colorectal Cancer in Middle East May Be Ineffective

Methods of Analyzing Pathways of Colorectal Cancer in Middle East May Be Ineffective

A majority of Middle Eastern colorectal cancer (CRC) cases was designated as part of the unassigned group.

Primary Melanoma Treatment Outcome Factors Identified

Primary Melanoma Treatment Outcome Factors Identified

Sex, LDH level, BRAF genotype, and ulceration status identified as being independent factors associated with treatment outcomes in melanoma.

Diagnostic Model Developed for Impending Death in Patients with Cancer

Diagnostic Model Developed for Impending Death in Patients with Cancer

A diagnostic model for impending death within 3 days was developed for patients with cancer.

Modified 2/1 Sunitinib Schedule May Be Safer in Renal Cell Carcinoma

Modified 2/1 Sunitinib Schedule May Be Safer in Renal Cell Carcinoma

Patients with metastatic renal cell carcinoma who transitioned to a modified 2/1 schedule of sunitinib experience an improved safety profile.

Febuxostat Superior to Allopurinol for Prevention of Tumor Lysis Syndrome

Febuxostat Superior to Allopurinol for Prevention of Tumor Lysis Syndrome

Febuxostat achieved a significant serum uric acid control in patients with hematologic malignancies at tumor lysis syndrome risk.

Comparison of Two S-1 Plus Cisplatin Dosing Schedules Shows No Survival Advantage

Comparison of Two S-1 Plus Cisplatin Dosing Schedules Shows No Survival Advantage

No difference in overall survival and either can be used as first-line treatments for patients with advanced gastric cancer.

Racial Differences Persist in Cause-specific Mortality in Breast Cancer

Racial Differences Persist in Cause-specific Mortality in Breast Cancer

While breast cancer-specific mortality among older women has improved across all races in recent years, other cause-mortality has not.

Improved Treatment Decisions Linked to Geriatric Consultations

Improved Treatment Decisions Linked to Geriatric Consultations

Geriatric assessments provided aid in making treatment decisions for older patients with cancer.

Many Colorectal Cancers Caused by Inherited Genetic Mutations

Many Colorectal Cancers Caused by Inherited Genetic Mutations

More than a third of colorectal cancers diagnosed in younger patients are caused by inherited gene mutations.

Quality of Life Linked with Physical, Psychological Symptoms in Cancer

Quality of Life Linked with Physical, Psychological Symptoms in Cancer

Quality of life (QoL) was found to be linked to physical and psychological symptoms in patients with advanced cancer.

Evaluating Evolution of Incidence Rates of Hodgkin Lymphoma Subtypes

Evaluating Evolution of Incidence Rates of Hodgkin Lymphoma Subtypes

Recent declines in nodular sclerosis (NS) rates represented true incidence changes in Hodgkin lymphoma (HL).

Lidocaine May Benefit Breast Cancer Survivors Who Experience Dyspareunia

Lidocaine May Benefit Breast Cancer Survivors Who Experience Dyspareunia

Breast cancer survivors with menopausal dyspareunia can have comfortable intercourse after applying liquid lidocaine.

Adding Bevacizumab to Paclitaxel Does Not Improve Survival in Angiosarcoma

Adding Bevacizumab to Paclitaxel Does Not Improve Survival in Angiosarcoma

Paclitaxel alone and paclitaxel plus bevacizumab are both active as treatments for patients with advanced angiosarcoma.

Frequent, Actionable MET Gene Mutations Found in Pulmonary Sarcomatoid Carcinoma

Frequent, Actionable MET Gene Mutations Found in Pulmonary Sarcomatoid Carcinoma

Mutational events that lead to MET exon 14 skipping may be targetable events in pulmonary sarcomatoid carcinoma (PSC).

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