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In Breast Cancer, Goserelin Protects Against Ovarian Failure

In Breast Cancer, Goserelin Protects Against Ovarian Failure

For patients with breast cancer, use of the gonadotropin-releasing hormone agonist, goserelin, protects against ovarian failure.

Soligenix to Enroll Additional Subjects in SGX942 Trial for Oral Mucositis

Soligenix to Enroll Additional Subjects in SGX942 Trial for Oral Mucositis

SGX942 is being evaluated as a treatment for oral mucositis in patients receiving chemoradiotherapy for head and neck cancer.

Cytarabine Plus Amonafide L-Malate Shows Similar Efficacy in Leukemia to Daunorubicin

Cytarabine Plus Amonafide L-Malate Shows Similar Efficacy in Leukemia to Daunorubicin

Treatment with amonafide L-malate in combination with cytarabine did not improve response rate in secondary acute myeloid leukemia (AML).

Correlated Spectroscopy Can Identify Changes in BRCA Carriers

Correlated Spectroscopy Can Identify Changes in BRCA Carriers

Use of localized correlated spectroscopy (COSY) shows significant changes in women with BRCA1 and BRCA2 mutations.

Opdivo Approved for Advanced Squamous Non-Small Cell Lung Cancer

Opdivo Approved for Advanced Squamous Non-Small Cell Lung Cancer

The FDA has approved Opdivo (nivolumab) for the treatment of patients with advanced (metastatic) squamous non-small cell lung cancer (NSCLC).

Adding Adjuvant Iriniotecan to 5FU/LV Not Effective for Resected Rectal Cancer

Adding Adjuvant Iriniotecan to 5FU/LV Not Effective for Resected Rectal Cancer

Postoperative irinotecan should not be added to a fluorouracil plus leucovorin adjuvant regimen for treatment of resected stage II-III rectal cancer.

Addition of Lenalidomide to Docetaxel, Prednisone Not Effective for mCRPC

Addition of Lenalidomide to Docetaxel, Prednisone Not Effective for mCRPC

Overall survival with combination lenalidomide, docetaxel, and prednisone was worse in metastatic castration-resistant prostate cancer (mCRPC).

Current Guidelines on Benign Thyroid Nodules Challenged

Current Guidelines on Benign Thyroid Nodules Challenged

Benign thyroid nodules are common, and research suggests they don't need to be monitored as closely as current guidelines recommend.

Novel Risk Score Could Identify Melanoma Risk

Novel Risk Score Could Identify Melanoma Risk

A novel risk score may be able to identify patients who are at risk for developing melanoma.

Ipilimumab Plus Dacarbazine Provide Survival Benefit in Advanced Melanoma

Ipilimumab Plus Dacarbazine Provide Survival Benefit in Advanced Melanoma

Ipilimumab plus dacarbazine provide a durable survival benefit at 5 years in patients treated for advanced melanoma.

Patients Prefer Physicians Conveying Positivity

Patients Prefer Physicians Conveying Positivity

Patients prefer physicians who convey a more optimistic message, and perceive in them a higher level of compassion.

Maintenance Sunitinib Safe, Effective for Extensive-Stage Small-Cell Lung Cancer

Maintenance Sunitinib Safe, Effective for Extensive-Stage Small-Cell Lung Cancer

Maintenance sunitinib after chemotherapy is safe and improves progression-free survival in extensive-stage small-cell lung cancer (SCLC).

High Resection Rates in Pancreatic Cancer with mFOLFIRINOX, Aggressive Surgery

High Resection Rates in Pancreatic Cancer with mFOLFIRINOX, Aggressive Surgery

Modified fluorouracil, leucovorin, irinotecan, and oxaliplatin (mFOLFIRINOX) with aggressive surgery demonstrates high resection rates in pancreatic cancer.

For NSCLC, L858R Mutation in Circulating Free DNA Is Prognostic Marker

For NSCLC, L858R Mutation in Circulating Free DNA Is Prognostic Marker

For patients with non-small-cell lung cancer (NSCLC), the L858R mutation in circulating free DNA seems to be a prognostic marker.

Disease Progression of Mantle Cell Lymphoma After Ibrutinib Associated with Poor Outcome

Disease Progression of Mantle Cell Lymphoma After Ibrutinib Associated with Poor Outcome

Outcome of patients with mantle cell lymphoma who experience disease progression following ibrutinib therapy is poor.

Oral Bisphosphonates Linked with Lower Endometrial Cancer Risk

Oral Bisphosphonates Linked with Lower Endometrial Cancer Risk

For postmenopausal women, oral bisphosphonate use is associated with a reduction in the risk of endometrial cancer.

Gene Mutations Found in Leukemia Increase with Age

Gene Mutations Found in Leukemia Increase with Age

An increase in genetic mutations that could trigger leukemia seems to be an inevitable part of aging.

Neoadjuvant Cetuximab Plus Chemo May Be Effective for Unresectable Squamous Cell Carcinomas

Neoadjuvant Cetuximab Plus Chemo May Be Effective for Unresectable Squamous Cell Carcinomas

Neoadjuvant cetuximab with platinum salt and fluorouracil shows good response in elderly unresectable locally advanced non-melanoma skin cancer.

Adding Cyclophosphamide to Standard Prostate Cancer Therapy Provides No Benefit

Adding Cyclophosphamide to Standard Prostate Cancer Therapy Provides No Benefit

Adding cyclophosphamide to docetaxel and prednisone for treatment of castration-resistant prostate cancer (CRPC) does not seem to provide any additional benefit.

Body Mass Index Predicts Survival in Metastatic Clear Cell Renal Cell Carcinoma

Body Mass Index Predicts Survival in Metastatic Clear Cell Renal Cell Carcinoma

Body mass index (BMI) predicts survival and overall response rates in patients with metastatic clear cell renal cell carcinoma.

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