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SGO 2017 Coverage

Hypermethylation of DNA Repair Genes in Ovarian Carcinoma

Hypermethylation of DNA Repair Genes in Ovarian Carcinoma

Hypermethylation of HRR-associated genes was not associated with improved survival in ovarian cancer.

Sentinel Lymph Node Mapping Cost-effective in Endometrial Carcinoma

Sentinel Lymph Node Mapping Cost-effective in Endometrial Carcinoma

Study data suggest that SLN mapping is more cost-effective and more efficacious than routine LND or selective LND.

Elderly Patients and Treatment Tolerance in Phase 1 Trials

Elderly Patients and Treatment Tolerance in Phase 1 Trials

Study results suggest that carefully selected elderly patients with recurrent or refractory gynecologic malignancy should be enrolled in phase 1 trials.

Patients With Ovarian Cancer Rank Nausea as Most Concerning Chemotherapy Side Effect

Patients With Ovarian Cancer Rank Nausea as Most Concerning Chemotherapy Side Effect

Patients with newly diagnosed ovarian cancer rank nausea as the most concerning side effect associated with chemotherapy.

Combined Liquid Pap and CT-DNA Testing May Detect Ovarian Cancer

Combined Liquid Pap and CT-DNA Testing May Detect Ovarian Cancer

Combined liquid-based Pap and CT-DNA may be a new method for tumor-derived driver mutation screening in primary ovarian carcinoma.

Reduction Strategies Improve Surgical Site Infection Rate After Colon Surgery

Reduction Strategies Improve Surgical Site Infection Rate After Colon Surgery

The results of this study show that implementation of strategies to reduce SSI can improve SSI rates, despite risk factors for infection.

Chemotherapy Fails To Prolong Survival in Low-grade Serous Ovarian Cancer

Chemotherapy Fails To Prolong Survival in Low-grade Serous Ovarian Cancer

Adjuvant platinum-based chemotherapy did not improve survival in women with low-grade serous ovarian cancer.

Adjuvant Chemotherapy Without Radiation Effective in Stage IB-IIA Cervical Cancer

Adjuvant Chemotherapy Without Radiation Effective in Stage IB-IIA Cervical Cancer

Data suggest that adjuvant chemotherapy without radiation may be an effective option for patients with stage IB to IIA cervical cancer with risk factors.

Adding Whole Pelvic Radiation to Chemotherapy May Prolong Survival in Advanced Cervical Cancer

Adding Whole Pelvic Radiation to Chemotherapy May Prolong Survival in Advanced Cervical Cancer

Data indicate that the addition of WPR to chemotherapy may provide a survival benefit, though prospective studies are needed to confirm these findings.

Aggressive Endometrial Cancer Subtypes More Common in African American Population

Aggressive Endometrial Cancer Subtypes More Common in African American Population

Study results suggest that aggressive molecular subtypes of endometrial cancer are more common among the African American population.

Burnout and Productivity Loss Among Gynecologic Oncologists

Burnout and Productivity Loss Among Gynecologic Oncologists

Gynecologic oncologists are at a particularly high risk for burnout compared with other specialties, suggesting a need for burnout prevention and wellness programs.

Hospital Readmission Reduction Program May Unfairly Penalize Hospitals

Hospital Readmission Reduction Program May Unfairly Penalize Hospitals

The Hospital Readmission Reduction Program may unfairly penalize hospitals if 30-day readmission rates are the only metric for care quality.

Isolated Tumor Cells and Routine Adjuvant Chemotherapy in Endometrial Cancer

Isolated Tumor Cells and Routine Adjuvant Chemotherapy in Endometrial Cancer

Patients with endometrial cancer who have isolated tumor cells identified by sentinel lymph node mapping should not routinely receive adjuvant chemotherapy.

BRCA1, RAD51C Methylation Linked to Response to PARP Inhibitors

BRCA1, RAD51C Methylation Linked to Response to PARP Inhibitors

BRCA1 and RAD51C methylation in ovarian carcinomas are associated with sensitivity to PARP inhibitors, such as rucaparib.

Cervical Cancer: SLN Biopsy Associated With Fewer Complications

Cervical Cancer: SLN Biopsy Associated With Fewer Complications

Sentinel lymph node biopsy was associated with fewer surgical complications, less lymphedema, and better quality of life.

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