Side Effect Management

Cancer Drug Addiction: Prospects for Integrated Therapeutic Management

Cancer Drug Addiction: Prospects for Integrated Therapeutic Management

The drug addiction strategy must be broadened to account for non-addicted cells, sensitive or resistant, that remain after therapy. Much as selection should favor the development of drug resistant tumor cell lineages, it should also favor lineages that are resistant to addiction.

Enzalutamide May Not Affect Seizure Incidence Among Men With Prostate Cancer, Seizure Risk Factors

Enzalutamide May Not Affect Seizure Incidence Among Men With Prostate Cancer, Seizure Risk Factors

The rate of confirmed seizures compared favorably with a retrospective study that noted a seizure rate of 2.8 per 100 patient-years among patients with mCRPC and risk factors for seizure who did not receive enzalutamide.

Beta-blockers May Prevent Stress-induced Lung Cancer Treatment Resistance

Beta-blockers May Prevent Stress-induced Lung Cancer Treatment Resistance

The results of this study support previous findings that psychological distress is associated with an increased risk of mortality among patients with lung cancer.

More Than 25% of Patients With Sarcoma Have Anxiety or Depression

More Than 25% of Patients With Sarcoma Have Anxiety or Depression

Researchers at the Seattle Cancer Care Alliance used email and web screening to determine patient quality of life and psychological comorbidities after a sarcoma diagnosis.

Exercise May Mitigate Doxorubicin-related Cardiotoxicity

Exercise May Mitigate Doxorubicin-related Cardiotoxicity

Researchers injected Ewing sarcoma cells into mice to determine the effects of exercise on doxorubicin efficacy and treatment-related cardiotoxicity.

Novel Intervention May Improve Fear of Recurrence Among Cancer Survivors

Novel Intervention May Improve Fear of Recurrence Among Cancer Survivors

Researchers enrolled survivors of breast cancer, colorectal cancer, or melanoma to participate in ConquerFear or a control intervention, Taking-it-Easy, and to complete accompanying questionnaires.

Myeloma: Proteasome Inhibitors and IMiDs May Increase Risk of Cardiovascular Complications

Myeloma: Proteasome Inhibitors and IMiDs May Increase Risk of Cardiovascular Complications

Patients with underlying cardiovascular disease and/or baseline hypertension and coronary artery disease may be at a higher risk.

Long-term Eltrombopag Improves Outcomes in Chronic Immune Thrombocytopenia

Long-term Eltrombopag Improves Outcomes in Chronic Immune Thrombocytopenia

Previous studies show that eltrombopag treatment for 6 months or less effectively increases platelet counts and reduces bleeding among patients with chronic ITP.

Curative-intent Surgery for Cancer Increases Risk of New Persistent Opioid-use

Curative-intent Surgery for Cancer Increases Risk of New Persistent Opioid-use

The modern opioid epidemic is forcing health care providers and government agencies to reevaluate pain management, but there is a lack of data regarding the risk of opioid-misuse among vulnerable populations.

Radiation Therapy Increases 5-year Rate of Cardiac Events in Small-cell Lung Cancer

Radiation Therapy Increases 5-year Rate of Cardiac Events in Small-cell Lung Cancer

Researchers analyzed the outcomes of 7060 patients with SCLC from the SEER database to determine the rates of new CEs among patients treated with chemotherapy plus RT or chemotherapy alone.

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