VIEWPOINTS


Viewpoints are a collection of news and opinion articles that capture key research developments and important issues in the field of oncology.


A Call for a New Collaboration to Cure Melanoma

A Call for a New Collaboration to Cure Melanoma

In the not-too-distant future, several new combination therapies are expected, and they should represent an improvement not only in effectiveness, but in safety as well.

Psychological Stress Unlikely to Cause Breast Cancer

Psychological Stress Unlikely to Cause Breast Cancer

Results of a prospective study consisting of more than 105,000 women have shown "it is unlikely that stress is implicated in causation of breast cancer."

In Search of the Right Treatment Combinations for Multiple Myeloma

In Search of the Right Treatment Combinations for Multiple Myeloma

A pooled analysis of 3 combination drug regimens used to treat refractory/relapsed multiple myeloma reaffirms their safety, but does little to distinguish which approach works best.

Multiple Myeloma: Risk and Benefit Profile Assessment May Improve Outcomes

Multiple Myeloma: Risk and Benefit Profile Assessment May Improve Outcomes

Identifying and preventing drug-related toxicities with new combination therapies are paramount for both outcomes and quality of life issues.

Robotic Surgery for Prostate Cancer May Not Improve Quality of Life

Robotic Surgery for Prostate Cancer May Not Improve Quality of Life

Sexual function scores do not appear to differ between the 2 groups at 6 weeks or 12 weeks post-surgery, and no significant differences were found for bowel quality of life or pathological outcomes.

Evolutionary Logic May Aid the Development of Cancer Therapies

Evolutionary Logic May Aid the Development of Cancer Therapies

Humans can tolerate tumors in large or paired organs more easily than in small, critical organs, and the larger organs may therefore have evolved fewer mechanisms to defend against cancerous cells.

ASCO and SGO Issue New Guidelines for Treating Ovarian Cancer

ASCO and SGO Issue New Guidelines for Treating Ovarian Cancer

ASCO and the Society of Gynecologic Oncology jointly issued new clinical practice guidelines for the treatment of patients with ovarian cancer.

Q&A With Emmanuel Antonarakis, MD: AR-V7 "Liquid Biopsy" Can Avoid Unneeded Treatment, Curb Health Care Costs

Q&A With Emmanuel Antonarakis, MD: AR-V7 "Liquid Biopsy" Can Avoid Unneeded Treatment, Curb Health Care Costs

AR-V7 has been implicated in metastatic prostate tumor resistance to the androgen-receptor signaling (ARS) blockers abiraterone and enzalutamide.

Biomarkers May Identify Which Patients With Renal Cell Carcinoma Will Benefit From Nivolumab

Biomarkers May Identify Which Patients With Renal Cell Carcinoma Will Benefit From Nivolumab

Researchers at Johns Hopkins identified genes involved in tumor cell metabolism that may predict which patients with renal cell carcinoma are unlikely to respond to treatment with nivolumab.

Q & A: Lynn Schuchter, MD, Explains Common Concerns of Patients With Melanoma

Q & A: Lynn Schuchter, MD, Explains Common Concerns of Patients With Melanoma

Cancer Therapy Advisor interviewed Lynn M. Schuchter, MD, to discuss the questions frequently asked by patients with melanoma during both the diagnosis and treatment phases of care.

Cancer Stem Cells May Hold the Key to Understanding Drug Resistance

Cancer Stem Cells May Hold the Key to Understanding Drug Resistance

Understanding the signaling pathways of cancer stem cells could hold promise for treating resistant forms of cancer.

Precision Therapy Offers Promise for Renal Cell Carcinoma

Precision Therapy Offers Promise for Renal Cell Carcinoma

The therapeutic landscape of renal cell carcinoma (RCC) has improved over the last 10 years, and greater advances are expected.

The Future of the Biomedical Research Workforce in the United States

The Future of the Biomedical Research Workforce in the United States

As our aging workforce expands, a decreasing number of young investigators are applying for National Institute of Health (NIH) R01-equivalent grants.

Researchers Identify the "Cell of Origin" in Basal Cell Carcinoma

Researchers Identify the "Cell of Origin" in Basal Cell Carcinoma

Invasive basal cell carcinoma arises only from epidermal stem cells, according to a study published in Nature.

Statistical Significance, Uncertainty, and KEYNOTE-010

Statistical Significance, Uncertainty, and KEYNOTE-010

Readers should look for "anything that adds uncertainty to the analysis, including uncertainty in the measurements, differences in dropout rates among arms, missing data, and how they were handled in the analysis."

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