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IASLC 2018 Coverage

Follow our complete coverage of the International Association for the Study of Lung Cancer 2018 meeting in Toronto, Canada.

Potential Early Plasma Biomarker for RCC

Researchers found that doubling in KIM-1 plasma concentrations were associated with an increased risk of developing of RCC and poorer survival.

Red Flags About Anlotinib’s Efficacy

The VEGFR/EGFR inhibitor anlotinib prolonged PFS and OS in Chinese patients with NSCLC, but additional studies are needed to determine its benefit in other populations.

Ask the Experts: NSCLC

Cancer Therapy Advisor asked 2 experts to weigh in on recommended treatment modalities for patients with non-small cell lung cancer.

Ask the Experts: STS Clinical Insights

Cancer Therapy Advisor asked 2 experts to weigh in on the latest clinical insights into soft tissue sarcoma.

Ask the Experts: Waldenström Macroglobulinemia

Cancer Therapy Advisor asked 3 experts to weigh in on recommended treatment modalities for patients with Waldenström macroglobulinemia.

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Latest Features

The Identification of a Potential Early Plasma Biomarker for Kidney Cancer

The Identification of a Potential Early Plasma Biomarker for Kidney Cancer

Researchers found that doubling in KIM-1 plasma concentrations was associated with an increased risk of developing of RCC and poorer survival.

Despite Promising Trial Results, Skeptics Raise Red Flags About Anlotinib's Efficacy in Heavily Treated NSCLC

Despite Promising Trial Results, Skeptics Raise Red Flags About Anlotinib's Efficacy in Heavily Treated NSCLC

The VEGFR/EGFR inhibitor anlotinib prolonged PFS and OS in Chinese patients with NSCLC, but additional studies are needed to determine its benefit in other populations.

Talazoparib Found to Confer a Survival Advantage in BRCA1/2-Positive Breast Cancer

Talazoparib Found to Confer a Survival Advantage in BRCA1/2-Positive Breast Cancer

Oral treatment with talazoparib improved progression-free survival and some quality of life measures compared with standard chemotherapy.

BRCA1/Shieldin Double Mutations May Signal Resistance to PARP Inhibitors

BRCA1/Shieldin Double Mutations May Signal Resistance to PARP Inhibitors

Double mutants may predict resistance to PARP inhibitors and could also indicate sensitivity to alternative treatments.

"Impressive" CNS Responses With Osimertinib Compared With Standard EGFR-TKIs in Patients With CNS Metastases at Baseline

"Impressive" CNS Responses With Osimertinib Compared With Standard EGFR-TKIs in Patients With CNS Metastases at Baseline

A preplanned exploratory analysis in a subset of patients from the phase 3 FLAURA study with CNS metastases at baseline shows "impressive" clinical activity in the CNS.

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