Top News
Tepotinib Validated for NSCLC With MET Exon 14-Skipping Mutation
Hemodialysis Ups Kidney Cancer Death Risk
FDA Denies Accelerated Approval of Keytruda Plus Lenvima for Unresectable HCC
Inqovi, an Oral Therapy for Myelodysplastic Syndromes, Gets FDA Approval
WEE1 Kinase Inhibitor Improved PFS in TP53-Mutated Ovarian Cancer
GnRH Antagonist vs Agonist for Metastatic Prostate Cancer Tied With Lower Mortality
MRI Alone Cannot Replace Prostate Cancer Active Surveillance Biopsies
Cognitive Impairment Affects Survival Outcomes in Geriatric Patients Undergoing Allogeneic HCT
Trial Evaluating Pracinostat in AML Patients Unfit for Intensive Chemotherapy Discontinued
Negative Effects of Exercise Intolerance in Long-Term Cancer Survivors
Changes in Management of CLL Due to COVID-19 Noted in Italy
EDITORIAL ADVISORY BOARD
E. David Crawford, MD
Jeffrey M. Farma, MD
Featured
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Subset of Patients With Richter Syndrome May Obtain Long-Term Survival
Data from Spain add to the knowledge of Richter syndrome. -
A Missed Opportunity in Expanded Access Limits Real-World Insights
An expanded access protocol for gemtuzumab ozogamicin gathered only safety data, no efficacy data, limiting insights into real-world use. -
Antibody-Drug Conjugates: Cancer Therapies to Watch
There are up to 80 ADCs in clinical development with close to 600 ongoing trials. -
Can Advocacy Groups Provide Useful Patient-Centered Data?
A survey presented during ASCO20 found that patients who considered themselves adequately informed felt “in control” most days. -
Machine Learning May Predict Patient Satisfaction After Breast Reconstruction
Race and ethnicity were key data points collected from the cohort and tracked with outcomes. -
Could Checkpoint Blockade Be Useful in Non-Hodgkin Lymphoma After All?
A study suggested that the immunotherapy could be sensitizing non-Hodgkin lymphoma patients to subsequent therapies. -
Direct-to-Drug Screening Tool Allows for Precision Medicine in Multiple Myeloma
An assay from Mayo Clinic researchers screens multiple myeloma drugs to see how cells with different biomarkers and pretreatment histories react.
More Features
PSA Density Plus MRI May Improve Detection of Clinically Significant Prostate Cancer
Combining PSA density with prostate MRI findings improves the predictive performance of PI-RADS in men without a prior prostate cancer diagnosis.
Treating Strategies for Patients With Relapsed/Refractory Acute Myeloid Leukemia
Although numerous clinical studies have aimed to treat AML, most results have been disappointing, according to authors of a publication in Blood.
New ASCO Clinical Guidelines on Management of Cancer Cachexia
The American Society of Clinical Oncology published new clinical guidelines on the management of cachexia in adults with advanced cancer.
4Kscore May Help Predict Adverse Pathology at Radical Prostatectomy
In a study, a higher 4Kscore was significantly associated with a 16% greater risk of biochemical recurrence of prostate cancer following radical prostatectomy.
When COVID-19 Meets CLL: Limited Evidence Offers Some Hope for Good Outcomes
A recent small study is hypothesis generating and highlights the need for COVID-19-related studies with large cohorts of CLL patients.
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