Top News
COBRA Study to Test ctDNA as Biomarker for Adjuvant Chemotherapy Benefit in Colon Cancer
Total Body Irradiation vs Chemotherapy Conditioning for Pediatric Acute Lymphoblastic Leukemia
Tivozanib and Durvalumab Doublet Regimen Is Well-Tolerated in HCC
Study Finds Similar Outcomes in Patients With, Without IBD and Rectal Cancer
New Clinical Guidelines Address Best Practices for Primary Systemic Therapy in Early-Stage Breast Cancer
Uncertainties Surround Optimal Dosing of Cytarabine in AML
Oral Azacitidine to Improve Survival in First-Remission Acute Myeloid Leukemia
New Clinical Decision Tool Predicts Survival Outcomes in Early-Stage TNBC
Study Finds Low Adherence to Lenalidomide Therapy in Multiple Myeloma
PARP Inhibition Associated With Increased Risk for Secondary MDS, AML
Advanced, Fatal Prostate Cancer Linked to Diet
EDITORIAL ADVISORY BOARD
E. David Crawford, MD
Jeffrey M. Farma, MD
Featured
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Use of Commercial Genomic Testing for Prostate Cancer ‘Highly Variable’ in the United States
Investigators evaluated a large sample of commercially insured patients with prostate cancer to assess use of tissue-based gene expression testing. -
Lung SCC Highly Mutated yet Homogenous Across Diverse Demographic Populations
Investigators used next-generation sequencing to characterize the genomic profile of squamous cell carcinoma (SCC) in 26 Colombian patients with lung SCC. -
Biosimilars in Cancer Care: Insights From 2020 and Expectations for 2021
Sean McGowan, senior director of Biosimilars at AmerisourceBergen, and Brian Ansay, senior vice president of Sales and Corporate Services at ION Solutions, review 2020 biosimilar trends in oncology and forecast what is ahead in 2021. -
T-VEC Shows Promise as Neoadjuvant Therapy in Melanoma
Investigators compared recurrence-free survival and overall survival outcomes in patients randomly assigned to receive neoadjuvant talimogene laherparepvec (T-VEC) followed by immediate surgery or surgery alone. -
Sodium Bicarbonate Associated With Enhanced GVL Effect in AML Following Allo-HSCT
Investigators assessed sodium bicarbonate’s viability as a pharmacologic strategy in mouse models and humans with acute myeloid leukemia. -
Considering Rehabilitation for Physical or Cognitive Deficits Associated With Cancer
This fact sheet delineates rehabilitation’s role in assuaging physical and cognitive deficits associated with cancer. -
Expanded Access Programs Deliver Real-World Efficacy Data
Efficacy data from expanded access programs were reported at ASH 2020, but whether these data will inform regulatory decisions remains to be seen.
More Features
6 Emotional Health Concerns of Oncologists During the COVID-19 Pandemic
Researchers have found a concerning level of distress in oncologists as a result of the COVID-19 pandemic that needs to be addressed so that they can better treat their patients and safeguard their own mental health.
A Statistical Fallacy Might Mar Study Findings on Bevacizumab in Melanoma
“‘Trended strongly’ is code for ‘we failed to meet statistical significance,’” remarked one expert, when she was asked to scrutinize the conclusions of a recent post hoc analysis.
A Tool Meant to Catch Distress in Patients With Breast Cancer May Overlook the True Needs of Black Women
The pitfall of self-reported stress levels is that the baseline stress for some people is so high, a cancer diagnosis doesn’t even register.
Study Shows Convalescent Plasma Is Beneficial for COVID-19 Patients With Hematological Malignancies
Despite mixed evidence for the general population, cumulative research reveals dramatic improvement with convalescent plasma for blood cancer patients, especially when given early.
Update on PD-1/PD-L1 Inhibitors in Extensive-Stage Small Cell Lung Cancer
PD-1/PD-L1 inhibitors offer an improvement over standard of care in SCLC, but there is still a long way to go.
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