Underdosing in Patients With Cancer and Obesity: A Thing of the Past?
New guidelines recommend using the full approved doses of immunotherapy and targeted therapies for patients with cancer and obesity.
All articles by Agata Boxe
Data From the CAPTIVATE Study’s uMRD Cohort Suggest Role for Fixed-Duration Therapy in CLL/SLL [Q&A]
John N. Allan, MD, a lead author of the CAPTIVATE study, discusses the findings from the uMRD cohort and their implications for the CLL/SLL paradigm.
Lung SCC Highly Mutated yet Homogenous Across Diverse Demographic Populations
Investigators used next-generation sequencing to characterize the genomic profile of squamous cell carcinoma (SCC) in 26 Colombian patients with lung SCC.
A Statistical Fallacy Might Mar Study Findings on Bevacizumab in Melanoma
“‘Trended strongly’ is code for ‘we failed to meet statistical significance,’” remarked one expert, when she was asked to scrutinize the conclusions of a recent post hoc analysis.
NCI-MATCH Trial Identifies Actionable Alterations in More Than One-Third of Patients With Cancer
Researchers have identified actionable alterations in nearly 38% of patients with cancer, and almost 18% of patients were assigned to treatments based on their molecular profiling results.
Tepotinib Yields High Partial Response Rates in NSCLC With MET Alterations
The MET alteration occurs in 3% to 4% of patients with the condition.
Industry-Funded Study Suggests There Is No Association Between TCI Use and Increased Skin Cancer Risk in Atopic Dermatitis
Observational study design and conflicts of interest prevent researchers from determining whether the FDA-mandated black box warning is warranted.
How the Coronavirus Pandemic May Affect Cancer Clinical Trials
Risks of moving clinical trials online include missing key information about the patient experience — and higher dropout rates could also impair the overall quality of trials.
G-CSF Appears Safe in CAR-T–Treated Patients With Refractory/Relapsed B-Cell Lymphoma
The treatment reduced hospital stay but not neutropenia duration or infection rate.
Study Points to a Rise in Renal Carcinomas in Children
The increase is thought to be related to environmental factors.
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