Prostate Cancer and Testosterone Replacement Therapy
A population-based study showed no association between total prostate cancer risk and testosterone replacement therapy (TRT).
All articles by Alexander M. Castellino, PhD
Hodgkin Lymphoma Survivors at Risk for Second Cancers
Survivors with a family history of colorectal, breast, and lung cancer were at a significantly higher risk of similar second cancers.
The Rising Trend of Colorectal Cancer in Young Adults
Compared with adults born in around 1950, those born around 1990 are at a 2-fold higher risk for colon cancers and a 4-fold higher risk for rectal cancers.
Bendamustine-triplet in Front-line Multiple Myeloma
The combination of bendamustine, bortezomib, and dexamethasone was reported to be effective in achieving overall response rates in myeloma.
Weight Gain: A Risk Factor for Postmenopausal Breast Cancer
While women who lost more than 5 kg after age 18 were at a 23% reduced risk for breast cancer, those who gained more than 30 kg were at a 32% increased risk.
More Research Needed to Overcome Challenges in Targeting KRAS in NSCLC
KRAS is commonly mutated in non-small cell lung cancer (NSCLC), but targeting KRAS directly has been unsuccessful.
Liquid Biopsies Genotype Advanced Lung Cancer Reliably, Swiftly
A liquid biopsy or simple blood test can reliably and swiftly genotype 2 key genes associated with advanced non-small cell lung cancer.
Farletuzumab Shows Limited Efficacy in Relapsed Ovarian Cancer
Farletuzumab, did not meet its primary endpoint in first platinum-sensitive relapse of ovarian cancer. But in a subset of patients, risk of progression was significantly reduced.
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