Tumor lysis syndrome
Tumor Lysis Syndrome (TLS) Also known as: Uric acid nephropathy, spontaneous TLS, acute renal failure 1. Description of the problem Tumor lysis syndrome (TLS) is defined by the metabolic derangements of hyperuricemia, hyperphosphatemia, hyperkalemia, hypocalcemia and acute renal failure that occur in the setting of rapid tumor destruction. When cellular lysis occurs (either spontaneously or…