Beckwith-Wiedmann Syndrome
Are You Confident of the Diagnosis? Beckwith-Wiedemann syndrome (BWS) is a syndrome of somatic overgrowth and a susceptibility to embryonal tumors. Diagnosis is usually made on clinical grounds, given the extreme heterogeneity of possible presentations, ranging from mild cutaneous involvement to intrauterine death. Diagnosis, however, is often difficult and often is aided by molecular testing.…
