Researchers sought to determine the recommended dose, safety, efficacy, pharmacokinetics, and pharmacodynamics of acalabrutinib in patients with symptomatic untreated CLL.
The proportion of childhood medulloblastomas varied widely between countries, offsetting the low proportion of low-grade astrocytomas in several countries.
Researchers found that low grade irAEs after anti-PD-1 therapy were more common than previously reported and frequently persist after prolonged follow-up.
The largest increase in cancer diagnosis at age 65 years was in stage I for all breast cancer, colon cancer, prostate cancer, and lung cancer.
An open-label, phase 2 trial was conducted at 10 centers in France and enrolled patients with sympotomatic, measurable newly diagnosed multiple myeloma.
CEST involves contouring the contralateral esophagus as an avoidance structure to guide a steep dose falloff gradient across the esophagus.
The trial found that the combination improved outcomes in patients with locally advanced rectal cancer compared with standard chemoradiotherapy, surgery, and adjuvant chemotherapy.
Researchers found that the therapy did not improve EFS or OS in high-risk patients and also led to an increase in toxic side effects.
Investigators analyzed the association between hepatic SOS and short-term application of 6-TG in 3983 pediatric ALL patients.
Melanoma excised with Mohs micrographic surgery, those treated at academic and higher-volume facilities had improved long-term survival.
