Cynthia Gauger, Author at Cancer Therapy Advisor

Cynthia Gauger

All articles by Cynthia Gauger

Hemolytic Anemia Due to Hereditary Spherocytosis and other RBC Membrane Defects

OVERVIEW: What every practitioner needs to know Are you sure your patient has Hereditary Spherocytosis and other RBC membrane defects? What are the typical findings for this disease? The most common hemolytic anemias resulting from defects in the red cell membrane include Hereditary Spherocytosis (HS), Hereditary Elliptocytosis (HE), and Hereditary Pyropoikilocytosis (HPP). Hereditary Spherocytosis is…

Hemolytic Anemia Due to Enzyme Deficiencies

OVERVIEW: What every practitioner needs to know Are you sure your patient has hemolytic anemia due to enzyme deficiencies? What are the typical findings for this disease? Hemolytic anemias may be due to factors external to the red blood cell (e.g., circulating autoantibodies to RBCs in Immune mediated hemolysis) or factors intrinsic to the red…

Thalassemias

OVERVIEW: What every practitioner needs to know Thalassemia may be defined as a heterogeneous group of inherited disorders characterized by reduced or absent globin chain synthesis. It is the deleterious effects of the excessively produced globin subunits that damage the red cell precursors, leading to a microcytic hypochromic anemia of variable severity. The β-thalassemias are…

Iron deficiency

OVERVIEW: What every practitioner needs to know Are you sure your patient has iron deficiency anemia? What are the typical findings for this disease? Iron deficiency anemia is the most common nutritional deficiency in childhood. This disease is characterized by a microcytic anemia, which can be caused by decreased intake and/or increased loss of iron.…

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