Next-Generation Sequencing Panels Cost-Effective for Diagnosis of Hereditary Colorectal Cancer
A decision model finds that the higher cost of new sequencing methods is justified by their clinical benefits.
All articles by Greg Otis
Will Patient-Reported Outcomes Be Included in Oncology Product Labeling?
FDA, industry, and patients are talking, but agreement on how to include patient experiences in oncology product prescribing information remains elusive.
Cardiovascular Risk in Men with Prostate Cancer on GnRH Agonist Therapy
Study of prostate cancer patients finds that treatment with GnRH agonists, but not antiandrogens, increases risk of cardiovascular events and mortality.
Genetic Aberration Affects Response to Bortezomib in AL Amyloidosis
The t(11;14) translocation was associated with poorer response rates and shorter overall survival in patients treated with bortezomib-based regimens.
Crizotinib Provides Benefit for ALK-Rearranged NSCLC with Brain Metastases
A retrospective analysis of crizotinib data demonstrates control in advanced, metastatic disease, although brain metastases continued to progress.
Metformin Does Not Reduce Lung Cancer Risk
A large, retrospective cohort study found no evidence that metformin prevents lung cancer, although nonsmokers may find some benefit.
ASCO Announces Chronic Leukemia Treatment as Cancer Advance of the Year
The transformation of the treatment of chronic lymphocytic leukemia wins the Society’s accolade.
Genetic, Metabolic Factors Are Targets of Research in Renal Cell Carcinoma
Recent studies reveal the mechanisms underlying renal cell carcinoma (RCC) and suggest new therapeutic targets.
A New Approach to Assessing Liver Function in Hepatocellular Carcinoma
By analyzing data from international databases, researchers develop an alternative to the Child-Pugh system.
Vaccine Found Safe, Shows Promise Against Breast Cancer
A new DNA vaccine caused mild side effects and a robust immune response to a breast cancer cell antigen.
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