OVERVIEW: What every practitioner needs to know Are you sure your patient has drug hypersensitivity syndrome? What are the typical findings for this disease? Skin eruptions from medications are common. These reactions can occasionally be severe and have systemic manifestations. The more severe form of medication reaction is termed drug hypersensitivity syndrome (DHS) and is…
OVERVIEW: What every practitioner needs to know. Are you sure your patient has erythema multiforme? What are the typical findings for this disease? Erythema multiforme (EM) is an acute eruption characterized by fixed, targetoid skin lesions with or without mild mucosal lesions. EM historically was considered to be on a spectrum with Stevens-Johnson syndrome (SJS)…
Are You Confident of the Diagnosis? Characteristic findings on physical examination The diagnosis of Confluent and Reticulated Papillomatosis of Gougerot and Carteaud (CARP) is based on slightly scaly, often hyperpigmented, very thin, elongated plaques as well as papules that coalesce into plaques on the upper trunk and flanks. It can involve the neck, face and…
Are You Confident of the Diagnosis? Characteristic findings on physical examination Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis that presents with firm indurated nodules or plaques especially in areas with large amounts of fat such as cheeks, thighs, buttocks, upper arms and trunk (Figure 1). The stress of birth is usually the…
Are You Confident of the Diagnosis? Characteristic findings on physical examination Sclerema neonatorum (SN) is a very rare disorder of subcutaneous fat that manifests as broad firm areas of hard skin within the first few days after birth (rarely later in the neonatal period) and generally progresses to involve nearly all the subcutaneous and even…
