Identifying Treatment Failure in Patients With Chronic Myeloid Leukemia
One study’s results may be especially relevant for patients eligible for treatment discontinuation.
All articles by Jon Christensen
Can Vismodegib Induce Melanoma in Patients Treated for Basal Cell Carcinoma?
Two cases raise the question of whether abnormal activation of the hedgehog signaling pathway can lead to a protective effect on melanomas.
Could Switching to Interferon Avoid an Abnormal Ovarian Response in CML?
Among female patients with CML, fertility preservation with ovarian stimulation can be challenging if patients require continuation of TKIs until HSCT.
Myeloma: Proteasome Inhibitors and IMiDs May Increase Risk of Cardiovascular Complications
Patients with underlying cardiovascular disease and/or baseline hypertension and coronary artery disease may be at a higher risk.
NSCLC: Liquid Biopsy May Predict Patient Response to Immune Checkpoint Inhibition
Liquid biopsy can be useful in cases where small bronchial biopsies contain a low number of tumor cells, and the repeatability of liquid biopsies can offer new approaches for monitoring patients treated with immunotherapy.
BRCA1, RAD51C Methylation Linked to Response to PARP Inhibitors
BRCA1 and RAD51C methylation in ovarian carcinomas are associated with sensitivity to PARP inhibitors, such as rucaparib.
Cervical Cancer: SLN Biopsy Associated With Fewer Complications
Sentinel lymph node biopsy was associated with fewer surgical complications, less lymphedema, and better quality of life.
Burnout and Productivity Loss Among Gynecologic Oncologists
Gynecologic oncologists are at a particularly high risk for burnout compared with other specialties, suggesting a need for burnout prevention and wellness programs.
Hospital Readmission Reduction Program May Unfairly Penalize Hospitals
The Hospital Readmission Reduction Program may unfairly penalize hospitals if 30-day readmission rates are the only metric for care quality.
Isolated Tumor Cells and Routine Adjuvant Chemotherapy in Endometrial Cancer
Patients with endometrial cancer who have isolated tumor cells identified by sentinel lymph node mapping should not routinely receive adjuvant chemotherapy.
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