Joe Carcillo

All articles by Joe Carcillo

HUS/TTP, Thrombotic Thrombocytopenic Purpura, Hemolytic Uremic Syndrome, Secondary Thrombotic Microangiopathy, Disseminated Intravascular Coagulation, Thrombocytopenia-associated Multiple Organ Failure

1. Description of the problem What every clinician needs to know Patients who develop new-onset thrombocytopenia (unexplained by bone marrow suppression) and multiple organ failure commonly have a thrombotic microangiopathy, which, if unrecognized and not treated, leads to higher mortality than if recognized and treated. These microangiopathies are mediated in part by platelet thrombi due…

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