Thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura What every physician needs to know: Thrombotic thrombocytopenic purpura (TTP) is a severe, life-threatening disorder caused by extensive, systemic platelet adhesion and aggregation. TTP is a type of thrombotic microangiopathy. It is characterized by organ ischemia, profound thrombocytopenia, erythrocyte fragmentation, and severe deficiency of a plasma von Willebrand factor (VWF)-cleaving protease, ADAMTS-13…