Joel Moake

All articles by Joel Moake

von Willebrand Disease (VWD)

von Willebrand Disease (VWD) What every physician needs to know Von Willebrand factor (VWF) is a huge multimeric protein comprised of identical 280,000 Dalton monomeric subunits. VWF is critical in the initiation of hemostasis. VWF multimers are produced and secreted by endothelial cells (and platelets) and, because they bind to platelet glycoprotein (GP) I receptors,…

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