Karen Clarke

All articles by Karen Clarke

Staphylococcal infections; MRSA

Staphylococcal infections; MRSA I. What every physician needs to know. Staphylococcus aureus (S. aureus), a commensal organism that asymptomatically colonizes the nares, and to a lesser degree, the vagina, pharynx, axillae, and skin in about 30 percent of healthy people. The ability of S. aureus to gain entry to, and then cause illness in almost…

Necrotizing soft-tissue infections and gas gangrene

I. What every physician needs to know. Necrotizing cellulitis, myositis, and necrotizing fasciitis are types of necrotizing soft-tissue infections (NSTIs). NSTIs typically arise in fascia or muscle, rather than in the more superficial dermis or epidermis. The source of these infections is usually skin trauma or an existing lesion (such as an ulcer). These infections…

Periorbital cellulitis and orbital infections

I. What every physician needs to know. The classification of orbital infections is based on a five-tier system, which is as follows: Group I (periorbital cellulitis, which is also known as preseptal cellulitis), Group II (orbital cellulitis), Group III (subperiosteal abscess), Group IV (orbital abscess), and Group V (cavernous sinus thrombosis). Periorbital/preseptal cellulitis affects structures…

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