OVERVIEW: What every practitioner needs to know Are you sure your patient has Hereditary Spherocytosis and other RBC membrane defects? What are the typical findings for this disease? The most common hemolytic anemias resulting from defects in the red cell membrane include Hereditary Spherocytosis (HS), Hereditary Elliptocytosis (HE), and Hereditary Pyropoikilocytosis (HPP). Hereditary Spherocytosis is…
OVERVIEW: What every practitioner needs to know Are you sure your patient has hemolytic anemia due to enzyme deficiencies? What are the typical findings for this disease? Hemolytic anemias may be due to factors external to the red blood cell (e.g., circulating autoantibodies to RBCs in Immune mediated hemolysis) or factors intrinsic to the red…
OVERVIEW: What every practitioner needs to know Are you sure your patient has B12 or Folate Deficiency Anemia? What are the typical findings for this disease? Deficiencies of vitamin B12 and folate are causes of macrocytic anemia. However, most macrocytic anemias in children are not associated with either B12 or folate deficiency, but rather are…
OVERVIEW: What every practitioner needs to know Are you sure your patient has iron deficiency anemia? What are the typical findings for this disease? Iron deficiency anemia is the most common nutritional deficiency in childhood. This disease is characterized by a microcytic anemia, which can be caused by decreased intake and/or increased loss of iron.…
