Pulmonary alveolar proteinosis
Pulmonary alveolar proteinosis I. What every physician needs to know. Pulmonary alveolar proteinosis (PAP) is an exceedingly rare diffuse lung disease. It is characterized by abnormal accumulation of surfactant-related phopholipoprotein material within the alveoli. Classification and pathogenesis Significant advances in the understanding of the pathophysiology of PAP have occurred in the past decade, beginning with…