Melissa Elder, Author at Cancer Therapy Advisor

Melissa Elder

All articles by Melissa Elder

Familial Mediterranean Fever (FMF)

OVERVIEW: What every practitioner needs to know Are you sure your patient has Familial Mediterranean Fever? What are the typical findings for this disease? Familial Mediterranean fever (FMF) is the most common inherited periodic fever syndrome and predominantly affects people of Mediterranean origin. FMF is characterized by lifelong recurrent episodes of fever and illness due…

Hereditary Pediatric Fever Syndromes

OVERVIEW: What every practitioner needs to know Are you sure your patient has a hereditary periodic fever syndrome? What are the typical findings for this disease? Hereditary periodic fever (PFS) syndromesare rare defects of innate immunity characterized by inappropriate, uncontrolled and often spontaneous inflammation in the absence of autoimmunity or infection. The most common findings…

Non-bacterial Osteitis Syndromes: CRMO, SAPHO, Majeed, and DIRA

OVERVIEW: What every practitioner needs to know The spectrum of non-bacterial osteitis syndromes (NBO) includes several clinically distinguishable syndromes: – Chronic recurrent multifocal osteomyelitis (CRMO) – Synovitis, acne, pustulosis, hyperostosis syndrome (SAPHO) – Chronic recurrent multifocal osteomyelits and congenital dyserythropoietic anemia (Majeed syndrome) – Deficiency of the IL-1 receptor antagonist (DIRA) Are you sure your…

PFAPA

OVERVIEW: What every practitioner needs to know Are you sure your patient has PFAPA? What are the typical findings for this disease? PFAPA (periodic fever with aphthous stomatitis, pharyngitis and adenitis) is considered one of the periodic fever syndromes (PFS), which are autoinflammatory diseases characterized by inappropriate, uncontrolled and often spontaneous inflammation in the absence…

NOMID/CINCA

OVERVIEW: What every practitioner needs to know Are you sure your patient has NOMID/CINCA? What are the typical findings for these diseases? Neonatal-onset multisystem inflammatory disease (NOMID) or chronic infantile neurologic cutaneous and articular syndrome (CINCA) is an inherited periodic fever syndrome characterized by inappropriate, uncontrolled and often spontaneous inflammation in the absence of autoimmunity…

Muckle-Wells syndrome

OVERVIEW: What every practitioner needs to know Are you sure your patient has Muckle-Wells syndrome? What are the typical findings for this disease? Muckle-Wells syndrome is an inherited periodic fever syndrome characterized by lifelong recurrent episodes of fever and illness due to seemingly unprovoked inflammation in the absence of autoimmunity or infection. The most common…

TRAPS (Hybernian fever)

OVERVIEW: What every practitioner needs to know Are you sure your patient has TRAPS? What are the typical findings for this disease? Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is one of the hereditary periodic fever syndromes (HPFSs), now commonly called systemic autoinflammatory disorders, characterized by inappropriate, uncontrolled, and often spontaneous activation of the…

Periodic Fever Syndromes

OVERVIEW: What every practitioner needs to know Are you sure your patient has a periodic fever syndrome? What are the typical findings for these diseases? Periodic fever syndromes (PFS) are a group of rare autoinflammatory diseases characterized by inappropriate, uncontrolled, and often spontaneous signs and symptoms of inflammation. Recurrent fever ≥ 38°C is the cardinal…

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