Paul Graham Fisher

All articles by Paul Graham Fisher

High-grade Astrocytomas

OVERVIEW: What every practitioner needs to know Are you sure your patient has high-grade astrocytomas? What are the typical findings for this disease? High-grade gliomas (HGG), also referred to as “malignant gliomas,” represent highly aggressive tumors that arise throughout the neuraxis, but most commonly in the supratentorial compartment of the central nervous system (CNS). The…

Brainstem Gliomas

OVERVIEW: What every practitioner needs to know Are you sure your patient has diffuse intrinsic pontine glioma? What are the typical findings for this disease? Brainstem gliomas are a heterogeneous group of tumors. The majority (80%) are diffusely infiltrating gliomas of the ventral pons (diffuse intrinsic pontine glioma [DIPG]), ranging in grade from World Health…

Medulloblastoma/PNET

OVERVIEW: What every practitioner needs to know Are you sure your patient has a medulloblastoma or primitive neuroectodermal tumor? What are the typical findings for this disease? Primitive neuroectodermal tumors (PNET) are a diverse group of highly malignant, “small round blue cell” tumors and are biologically distinct. They are divided into peripheral PNET and central…

Ependymomas

OVERVIEW: What every practitioner needs to know Ependymoma is a rare central nervous system tumor affecting 2.0-2.3/million people in the United States, and occurring more commonly in children than adults. Symptoms of ependymoma are dependent on the location of the tumor, with intracranial tumors causing increased intracranial pressure, headache, ataxia, seizures, and nausea and vomiting,…

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