OVERVIEW: What every practitioner needs to know Are you sure your patient has B12 or Folate Deficiency Anemia? What are the typical findings for this disease? Deficiencies of vitamin B12 and folate are causes of macrocytic anemia. However, most macrocytic anemias in children are not associated with either B12 or folate deficiency, but rather are…
OVERVIEW: What every practitioner needs to know Thalassemia may be defined as a heterogeneous group of inherited disorders characterized by reduced or absent globin chain synthesis. It is the deleterious effects of the excessively produced globin subunits that damage the red cell precursors, leading to a microcytic hypochromic anemia of variable severity. The β-thalassemias are…
OVERVIEW: What every practitioner needs to know Are you sure your patient has Autoimmune Hemolytic Anemia? What are the typical findings for this disease? Autoimmune Hemolytic Anemia (AIHA) is characterized by antibody-induced erythrocyte destruction. The patient’s own antibodies are directed against antigens on their own red blood cells resulting in hemolysis and anemia. AIHA is…
