Acute lymphoblastic leukemia What every physician needs to know: Acute lymphoblastic leukemia (ALL) is a neoplasm involving precursor lymphoblasts committed to either the B-cell or T-cell lineage. ALL is primarily a disease of children, with about 75% of cases occurring in patients under 6 years of age. The incidence of ALL is about 2 per…
Adult T-cell leukemia/lymphoma What every physician needs to know: Adult T-cell leukemia/lymphoma (ATL) is a distinct subtype of mature or peripheral T-cell lymphomas associated with the human T-cell lymphotrophic virus type 1 (HTLV-1). HTLV-1 is a human retrovirus that is endemic in certain parts of the world, including the northern and southern islands of Japan,…
Acute graft-versus-host disease What every physician needs to know about acute graft-versus-host disease: Acute graft-versus-host-disease (acute GVHD) occurs when lymphocytes from another person are able to survive and proliferate in a patient; it is one of the most serious complications of allogeneic bone marrow transplantation (BMT). Rare causes of acute GVHD include maternal transfer of…
