Steve Fiorillo

All articles by Steve Fiorillo

Effects of Drugs Targeting Mitochondrial Respiration in Melanoma

Despite relying on glycolysis, there is growing evidence that many tumor types still have high levels of mitochondrial energy metabolism and functioning oxidative phosphorylation. One such subset of tumors is melanoma, potentially playing a role in both tumor progression and resistance to therapy. This has led researchers to wonder whether targeting mitochondrial respiration could be…

Telemedicine and Quality of Life in Patients With Lung Cancer

Telemedicine has become more crucial than ever in the continuing wake of the COVID-19 pandemic. Research from the US Centers for Disease Control and Prevention (CDC) showed that there was a 50% increase utilization of telehealth services in the first quarter of 2020 compared with 2019, and a 154% increase in week 13 of 2020…

Is There An Association Between DCIS and Breast Cancer Mortality?

How effective is surgical treatment for ductal carcinoma in situ (DCIS) at preventing an invasive recurrence of breast cancer? Treatment is intended to significantly lessen the lifetime risk of breast cancer and breast cancer-related mortality, but are patients diagnosed with DCIS still at risk for experiencing poor outcomes? A recent study in JAMA Network Open…

How Do Melanoma Comorbidities Affect Patient Treatment Preferences?

Comorbidities can have an impact on what you as a medical professional think is the best course of treatment for your patients. Can they also affect a patient’s thinking on treatment? Comorbidities such as cardiovascular disease, hypertension, and depression can contribute to how a patient’s body responds to treatment and its attendant stress. A recent…

How Can Disparities in Lung Cancer Screening Eligibility Be Addressed?

A significant amount of progress has been made in improving the treatment of lung cancer and patient outcomes. However, a number of disparities that can have an impact on these persist, including those affecting lung cancer screening. Lung cancer screening is an essential step toward effective treatment and improved survival,  but its success depends on…

Can the Type of Breast Cancer Surgery Affect Psychosocial Health in Young Patients?

Breast cancer is an incredibly fraught experience for patients. Even beyond the diagnosis and treatment, the experience can create emotional issues that linger long after remission. Patients can have issues related to body image that can dramatically affect their self-esteem and sexuality as they work to regain a sense of normality in their daily lives.…

Can Earlier Mammographic Screenings Affect Mortality Rates?

When should women begin getting mammograms? Guidance can vary based on an individual’s family history or other high-risk identifiers, but physicians advise that women get screened for breast cancer consistently by at least age 50. However, a recent study out of the United Kingdom suggests that starting breast cancer screenings earlier could have a large…

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