Large granular lymphocyte leukemia, rheumatoid arthritis, and Felty's syndrome
Large granular lymphocyte leukemia, rheumatoid arthritis, and Felty's syndrome What every physician needs to know: Large granular lymphocyte leukemia (LGL) is a lymphoproliferative disorder, marked by clonal expansion of large granular lymphocytes, usually T cell in origin (85%), with a minority that arise in the natural killer (NK) lineage (15%). Median age of onset is…