BREATH Trial Reduced Distress in Early Breast Cancer Survivors

Share this content:

the Cancer Therapy Advisor take:

The Breast Cancer E-Heath (BREATH) trial combined with care as usual (CAU) was associated with significantly less distress in patients compared to CAU alone, according to an article published online in Journal of Clinical Oncology.

The BREATH trial is a Web-based self-management intervention available to breast cancer survivors (BCSs) that provides support for the psychological adjustment after primary treatment. BREATH consists of 16 automated weekly modules covering issues survivors may face early on.

In this study, BCSs were assigned to receive CAU + BREATH (n = 70) or CAU alone (n = 80) 2 to 4 months post-treatment.

Results showed participants in the CAU + BREATH cohort experienced significantly less distress than those in the CAU alone group (−7.79; 95% CI: −14.31, −1.27; P=0.02), with a small-to-medium effect size (d=0.33). However, empowerment was not determined to be affected (−1.71; 95% CI: 5.20, −1.79; P=0.34).

Furthermore, it was observed that in low-distress BCSs, a higher number of individuals in the CAU + BREATH cohort (39 of 70 [56%]; 95% CI: 44.1, 66.8) displayed clinically significant improvement (P=0.03), compared with those in the CAU alone cohort (32 of 80 [40%]; 95% CI: 30.0, 51.0).

The authors noted that the reduced distress observed in patients primarily was not sustained during follow-up.

Breast Cancer E-Heath (BREATH) trial combined with care as usual associated with significantly less
Breast Cancer E-Heath (BREATH) trial combined with care as usual associated with significantly less distress compared to CAU alone.
The BREATH trial is a Web-based self-management intervention to support the psychological adjustment of women after primary treatment, by reducing distress and improving empowerment.
READ FULL ARTICLE From Ascopubs

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters



Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs