Screening for Breast Cancer in Elderly Women Questioned

Share this content:
Mammograms for those aged 69 to 75 could result in overtreatment.
Mammograms for those aged 69 to 75 could result in overtreatment.

Including women older than 70 in national breast cancer screening programs won't lead to a sharp reduction in advanced forms of the disease, according to researchers who published their study findings online in The BMJ.

Using data from the Netherlands Cancer Registry, the researchers identified all new cases of invasive and noninvasive (in situ) breast cancer among women between 69 and 75 years old. The women were diagnosed with the disease between 1995 and 2011.

Of the 25,500 cases identified, the researchers divided the women into three groups: those diagnosed before the introduction of the national screening program (1995 to 1997), those diagnosed afterwards (2003 to 2011), and those diagnosed in-between (1998 to 2002). The Leiden University researchers also included 13,000 women between 76 and 80 years old to track rates of breast cancer among older women not eligible for screening.

RELATED: Women Over 75 Still Benefit From Mammograms

New cases of early-stage breast cancer among women between 70 and 75 years old increased from 248.7 to 362.9 per 100,000 women after the national screening program was introduced. Although there was a drop in the number of new cases of advanced breast cancer, the absolute decrease was small, from 58.6 cases per 100,000 women before to 51.8 cases after the program started. In comparison, new cases of early-stage breast cancer fell slightly for women between 76 and 80 years old, but the number of new cases of advanced breast cancer was unchanged.

The researchers concluded that for every one advanced-stage cancer diagnosed by screening older women, about 20 overdiagnosed early-stage cancers are detected. They noted the overdiagnosis and treatment of breast cancer could take a significant toll on a woman's quality of life.

The researchers added that breast cancer treatments are expensive and may not provide older women, who are more vulnerable to side effects, significant health benefits. "Instead of using mass screening, the decision to participate in the screening program should be personalized, based on remaining life expectancy, breast cancer risk, functional status, and patients' preferences," the study authors said in a journal news release.

Reference

  1. "Effect of implementation of the mass breast cancer screening programme in older women in the Netherlands: population based study." The BMJ. doi: http://dx.doi.org/10.1136/bmj.g5410. September 14, 2014

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters



Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs