Cervical Cancer

USPSTF Updates Its Recommendations for Cervical Cancer Screening

USPSTF Updates Its Recommendations for Cervical Cancer Screening

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The US Preventive Services Task Force conducted a review of trials and cohort studies to support an update of its cervical cancer screening recommendations for women ages 21 to 65 and older.

Primary HPV testing may detect cervical neoplasms earlier and more accurately than cytology

For the past two decades, meta-analyses have suggested that HPV testing increases detection of pre-cancerous cervical lesions when compared to cytology.

Could HPV Testing Take the Place of the Pap for Cervical Cancer Screening?

Could HPV Testing Take the Place of the Pap for Cervical Cancer Screening?

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The confirmation of a positive HPV test appeared to be more predictive of a grade 2 or 3 cervical lesion than cytology screening alone.

Pembrolizumab FDA-Approved for the Treatment of Advanced Cervical Cancer

Pembrolizumab FDA-Approved for the Treatment of Advanced Cervical Cancer

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Pembrolizumab is the first anti-PD-1 therapy approved for the treatment of advanced cervical cancer.

Adjuvant Chemotherapy Non-Inferior to Chemoradiotherapy in Cervical Cancer

Adjuvant Chemotherapy Non-Inferior to Chemoradiotherapy in Cervical Cancer

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There were no significant differences in patterns of recurrence in the chemotherapy vs CCRT groups.

Cervical Cancer Treatment Regimens

View a detailed drug treatment regimen chart for cervical cancer, including therapies such as cisplatin, cisplatin + 5-FU, and more.

FDA Approves Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

FDA Approves Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

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Bevacizumab-awwb is a recombinant IgG1 monoclonal antibody that works by binding to vascular endothelial growth factor (VEGF) and inhibits angiogenesis.

Cervical Cancer Progression More Likely With HIV Infection

Cervical Cancer Progression More Likely With HIV Infection

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Women with HIV are more likely to experience progressive cervical changes, according to a study.

Phase 1b/2 Study of DPX-E7 + Cyclophosphamide in HPV-positive Cancers

Phase 1b/2 Study of DPX-E7 + Cyclophosphamide in HPV-positive Cancers

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Researchers are evaluating whether DPX-E7 vaccination is safe and will improve outcomes among patients with HPV-positive head and neck, cervical, or anal cancer.

ASCO Publishes Cervical Cancer Prevention Guideline

ASCO Publishes Cervical Cancer Prevention Guideline

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ASCO published global recommendations for the primary prevention of cervical cancer in the Journal of Global Oncology.

Adding Whole Pelvic Radiation to Chemotherapy May Prolong Survival in Advanced Cervical Cancer

Adding Whole Pelvic Radiation to Chemotherapy May Prolong Survival in Advanced Cervical Cancer

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Data indicate that the addition of WPR to chemotherapy may provide a survival benefit, though prospective studies are needed to confirm these findings.

Adjuvant Chemotherapy Without Radiation Effective in Stage IB-IIA Cervical Cancer

Adjuvant Chemotherapy Without Radiation Effective in Stage IB-IIA Cervical Cancer

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Data suggest that adjuvant chemotherapy without radiation may be an effective option for patients with stage IB to IIA cervical cancer with risk factors.

Cervical Cancer: SLN Biopsy Associated With Fewer Complications

Cervical Cancer: SLN Biopsy Associated With Fewer Complications

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Sentinel lymph node biopsy was associated with fewer surgical complications, less lymphedema, and better quality of life.

BRCA1, RAD51C Methylation Linked to Response to PARP Inhibitors

BRCA1, RAD51C Methylation Linked to Response to PARP Inhibitors

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BRCA1 and RAD51C methylation in ovarian carcinomas are associated with sensitivity to PARP inhibitors, such as rucaparib.

Maternal Cancer During Pregnancy Linked to Stillbirth, Neonatal Mortality

Maternal Cancer During Pregnancy Linked to Stillbirth, Neonatal Mortality

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Although rare, maternal cancer during pregnancy is associated with elevates risks of stillbirth and neonatal death.

Address of Women's Cancers Worldwide Critical for Global Health

Address of Women's Cancers Worldwide Critical for Global Health

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A series of 3 articles just published in The Lancet discuss the present and future challenges of breast and cervical cancers globally.

Less Frequent Cervical Cancer Screenings May Be Okay After HPV Vaccine

Less Frequent Cervical Cancer Screenings May Be Okay After HPV Vaccine

Women vaccinated with earlier versions of the human papillomavirus (HPV) vaccine may only need cervical cancer screening every five years.

Low Incidence of Cervical Cancer, CIN+ Among HPV-negative Women

Low Incidence of Cervical Cancer, CIN+ Among HPV-negative Women

Human papillomavirus (HPV)-negative women have low long-term incidence of cervical cancer and cervical intraepithelial neoplasia (CIN).

Patterns in PI3K Signaling Pathway Aberrations Evaluated

Patterns in PI3K Signaling Pathway Aberrations Evaluated

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Researchers argue that combination therapies targeting both mutations in the PI3K pathway and HER2 or hormone receptor overexpression should be evaluated across cancer types.

ASCO Issues New Guidelines Regarding Health Care Access for Patients With Invasive Cervical Cancer

ASCO Issues New Guidelines Regarding Health Care Access for Patients With Invasive Cervical Cancer

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New guidelines provide clinical practice recommendations for patients with cervical cancer in regions with "basic, limited, enhanced, and maximal" health care resources.

Fosaprepitant May Lower Risk of Emesis, Nausea in Women With Cervical Cancer

Fosaprepitant May Lower Risk of Emesis, Nausea in Women With Cervical Cancer

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Patients with cervical cancer who receive fosaprepitant in addition to palonosetron and dexamethasone may be less likely to experience emesis and nausea.

Co-testing May Detect Invasive Cervical Cancer Better Than HPV-only Screening

Co-testing May Detect Invasive Cervical Cancer Better Than HPV-only Screening

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Not only may co-testing help detect more cases of invasive cervical cancer, but it also may lower overall health care costs.

IMRT Associated With Fewer GI, GU Adverse Events in Cervical Cancer

IMRT Associated With Fewer GI, GU Adverse Events in Cervical Cancer

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Intensity-modulated radiation therapy (IMRT) is associated with fewer gastrointestinal and genitourinary adverse events and improved quality of life.

ACOG Recommends Primary HPV Screening as Alternative to Cytology in Those 25 Years and Older

ACOG Recommends Primary HPV Screening as Alternative to Cytology in Those 25 Years and Older

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New guidelines stated that screening with an FDA-approved primary HPV test could substitute cytology-based cervical cancer screening methods.

Bevacizumab Not Beneficial in Subset of Cervical Cancer Patients

Bevacizumab Not Beneficial in Subset of Cervical Cancer Patients

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By identifying patients with cervical cancer as low, intermediate, or high-risk, physicians can determine whether bevacizumab will provide survival benefit.

Adding Cediranib to Carboplatin, Paclitaxel May Improve Therapy Efficacy in Cervical Cancer

Adding Cediranib to Carboplatin, Paclitaxel May Improve Therapy Efficacy in Cervical Cancer

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Adding cediranib to carboplatin and paclitaxel may significantly improve efficacy in treatment of metastatic or recurrent cervical cancer.

Sonography, MRI Comparable for Cervical Cancer Staging

Sonography, MRI Comparable for Cervical Cancer Staging

Transvaginal sonography (TVS) is comparable to magnetic resonance imaging (MRI) for diagnosing and staging local cervical cancer.

Cervical Cancer Survival Influenced by Presence of Diabetes Mellitus

Cervical Cancer Survival Influenced by Presence of Diabetes Mellitus

Diabetes mellitus (DM) determined to be an independent unfavorable prognostic factor in Asian patients with early cervical cancer.

FDA Updates Safety Info for Topotecan Hydrochloride

FDA Updates Safety Info for Topotecan Hydrochloride

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The FDA has updated the safety labeling for Hycamtin injection by adding a boxed warning for severe myelosuppression.

Rates of Precancerous Cervical Lesions Declining in Young Women

Rates of Precancerous Cervical Lesions Declining in Young Women

Recent decline in cervical intraepithelial neoplasia and adenocarcinoma in situ (CIN2+) lesions were likely due to reduced screening.

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