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CYTOTEC
Hyperacidity, GERD, and ulcers
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Drug Name:

CYTOTEC Rx

Generic Name and Formulations:
Misoprostol 100mcg, 200mcg; tabs.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for CYTOTEC:

Prevention of NSAID-induced gastric ulcers.

Adult:

Take with food. 200mcg 4 times daily with meals (last dose at bedtime). May reduce dose if not tolerated.

Children:

Not established.

Contraindications:

Pregnancy.

Boxed Warning:

Abortifacient property. Do not give the drug to others.

Warnings/Precautions:

Can cause birth defects, abortion, premature birth or uterine rupture in pregnant women. For women of childbearing potential: negative serum pregnancy test within 2 weeks before starting therapy; begin on 2nd or 3rd day of next menstrual period; maintain contraception during therapy; give oral and written warnings on risks in pregnancy. Cardiovascular disease. Inflammatory bowel disease. Dehydration. Labor & delivery. Nursing mothers.

Pharmacological Class:

Prostaglandin E1 analogue.

Interactions:

Avoid magnesium-containing antacids (to reduce diarrhea risk). Concomitant oxytocic agents: not recommended.

Adverse Reactions:

Diarrhea, abdominal pain, headache, gynecological effects (eg, spotting, cramps), abortion, premature birth, birth defects, uterine rupture.

How Supplied:

Tabs 100mcg—60, 120; 200mcg—60, 100


Data provided by MPR.

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