Alzheimer's dementia:
Indications for: ADLARITY
Alzheimer's dementia.
Adult Dosage:
Apply to clean, dry, intact skin on the back (avoiding the spine). If needed, may apply to the upper buttocks or upper outer thigh. Press down firmly for 30secs. Do not use if patch is damaged, cut, or altered. Rotate application site every 2 weeks. Initially 5mg/day once weekly; may increase to max 10mg/day after 4–6 weeks. Replace the patch after 7 days. Switching from donepezil oral forms: see full labeling.
Children Dosage:
Not established.
ADLARITY Contraindications:
History of allergic contact dermatitis with previous use.
ADLARITY Warnings/Precautions:
Application-site skin reactions. Use during anesthesia. Cardiac conduction abnormalities. Peptic ulcer. Monitor for GI bleeding. Bladder outflow obstruction. Seizures. Asthma or COPD. Avoid long exposure to external heat. Pregnancy. Nursing mothers.
ADLARITY Classification:
Reversible acetylcholinesterase inhibitor (piperidine deriv).
ADLARITY Interactions:
Antagonizes anticholinergics. May potentiate succinylcholine-type muscle relaxants, similar neuromuscular blocking agents, other cholinesterase inhibitors, or cholinergic agonists (eg, bethanecol). Concomitant NSAIDs may increase risk of GI bleed.
Adverse Reactions:
Nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue, anorexia, ecchymosis; allergic contact dermatitis.
Generic Drug Availability:
NO
How Supplied:
Patch—4
