Indications for: ANORO ELLIPTA

Maintenance treatment of COPD.

Limitations of Use:

Not indicated for relief of acute bronchospasm or for treatment of asthma.

Adult Dosage:

1 inhalation once daily.

Children Dosage:

Not established.

ANORO ELLIPTA Contraindications:

Severe allergy to milk proteins. Use of LABA without inhaled corticosteroid (ICS) in those with asthma.

ANORO ELLIPTA Warnings/Precautions:

LABA as monotherapy (without ICS) for asthma can increase risk of asthma-related events. Do not initiate in rapidly deteriorating or life-threatening COPD episodes. Prescribe a short-acting, inhaled β2-agonist for acute symptoms; monitor for increased need. Do not exceed recommended dose. Avoid use with other long-acting β2-agonists. Discontinue if paradoxical bronchospasm occurs; use alternative therapy. Cardiovascular disorders (esp. coronary insufficiency, arrhythmias, hypertension). Convulsive disorders. Thyrotoxicosis. Hyperresponsiveness to sympathomimetics. Diabetes. Ketoacidosis. Narrow-angle glaucoma. Urinary retention. Prostatic hyperplasia. Bladder-neck obstruction. Risk of hypokalemia or hyperglycemia. Labor & delivery. Pregnancy. Nursing mothers: not recommended.

ANORO ELLIPTA Classification:

Anticholinergic + long-acting beta-2 agonist (LABA).

ANORO ELLIPTA Interactions:

Caution with concomitant strong CYP3A4 inhibitors (eg, ketoconazole, ritonavir, clarithromycin, conivaptan, indinavir, itraconazole, lopinavir, nefazodone, nelfinavir, saquinavir, telithromycin, troleandomycin, voriconazole), MAOIs, tricyclic antidepressants, drugs known to prolong the QT interval or within 2 weeks of discontinuing such agents (increased cardiac effects), K+-depleting diuretics. Antagonized by β-blockers; if needed, consider cardioselective agents. Additive effects with concomitant other anticholinergic-containing drugs; avoid.

Adverse Reactions:

Pharyngitis, sinusitis, lower respiratory tract infection, constipation, diarrhea, pain in extremity, muscle spasms, neck and chest pain; hypersensitivity reactions (discontinue if occurs).

Generic Drug Availability:


How Supplied:

Dry pwd inhaler—30 doses