Migraine and headache:
Indications for ASCOMP w. CODEINE:
Tension (or muscle contraction) headache.
1–2 caps every 4 hours, as needed; max 6 caps/day. Use lowest effective dose for shortest period of time.
NSAID allergy. Porphyria. Bleeding or coagulation disorders. Peptic ulcer.
Renal or hepatic impairment; monitor liver/renal function tests. Acute abdomen. Asthma. Bleeding disorders. Head injury. Increased intracranial pressure. Impaired thyroid or adrenocortical function. GI or GU obstruction. Ultra-rapid metabolizers of codeine (may experience overdose symptoms). Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Opioid + barbiturate + salicylate + stimulant.
CNS effects may be enhanced by MAOIs. Concomitant corticosteroids: withdrawal of corticosteroid may result in salicylism. May potentiate oral anticoagulants, oral antidiabetics and insulin, 6-mercaptopurine and methotrexate, NSAIDs, other narcotic analgesics, alcohol, general anesthetics, tranquilizers, sedative-hypnotics, other CNS depressants. May diminish effects of uricosuric agents.
Drowsiness, dizziness, intoxicated feeling, GI upset/pain.