Bleeding disorders:

Indications for: CYKLOKAPRON

Short-term use in hemophilia to reduce or prevent hemorrhage, and reduce the need for replacement therapy during and following tooth extraction.

Adults and Children:

Give by IV inj. Max injection rate: 1mL/min. Pre-extraction: 10mg/kg; post-op: 10mg/kg 3–4 times daily for 2–8 days. Renal impairment: serum creatinine 1.36–2.83mg/dL: 10mg/kg twice daily; 2.83–5.66mg/dL: 10mg/kg once daily; >5.66mg/dL: 10mg/kg every 48hrs or 5mg/kg every 24hrs.

CYKLOKAPRON Contraindications:

Subarachnoid hemorrhage. Active intravascular clotting.

CYKLOKAPRON Warnings/Precautions:

For IV use only. Confirm the correct route of administration. Therapy longer than 3 months: do ophthalmologic exam at regular intervals; discontinue if visual changes occur. Risk of seizures esp. during cardiovascular surgery or inadvertent neuraxial administration. Renal impairment: reduce dose. History of thromboembolic disease. Pregnancy. Nursing mothers.

CYKLOKAPRON Classification:

Plasminogen activation inhibitor.

CYKLOKAPRON Interactions:

Avoid concomitant Factor IX complex concentrates, Anti-inhibitor coagulant concentrates, or hormonal contraceptives; increased risk of thrombosis. Do not mix with solutions containing penicillin or with blood products.

Adverse Reactions:

GI upset, allergic dermatitis, giddiness, hypotension, visual abnormalities; thromboembolic events (rare), dizziness, convulsions, anaphylaxis.

How Supplied:

Single-dose amps (10mL)—1, 10; single-dose vials (10mL)—10


10ml of 100mg vial (Qty: 1)
Appx. price $16