Actinic keratoses:
Indications for: EFUDEX CREAM
Multiple actinic or solar keratoses. Superficial basal cell carcinoma when conventional therapy is impractical (5% only); see full labeling.
Adult Dosage:
Keratoses: Apply twice daily until erosion occurs (usually 2–4 wks). Basal cell carcinoma (5% only): Apply twice daily, usually for 3–6 weeks (obliteration may take 10–12 weeks).
Children Dosage:
Not established.
EFUDEX CREAM Contraindications:
Dihydropyrimidine dehydrogenase (DPD) deficiency. Pregnancy.
EFUDEX CREAM Warnings/Precautions:
Do not apply into eyes, nose, or mouth. Avoid mucous membranes, occlusion, ulcerated/inflamed skin, exposure to UV light. Wash hands after application if fingers were used. Advise patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended.
See Also:
EFUDEX CREAM Classification:
Antimetabolite.
Adverse Reactions:
Burning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, ulceration; leukocytosis.
Generic Drug Availability:
YES
How Supplied:
Soln (w. drop dispenser)—10mL, 25mL; Crm—40g
Melanoma and other skin cancers:
Indications for: EFUDEX CREAM
Multiple actinic or solar keratoses. Superficial basal cell carcinoma when conventional therapy is impractical (5% only); see full labeling.
Adult Dosage:
Keratoses: Apply twice daily until erosion occurs (usually 2–4 wks). Basal cell carcinoma (5% only): Apply twice daily, usually for 3–6 weeks (obliteration may take 10–12 weeks).
Children Dosage:
Not established.
EFUDEX CREAM Contraindications:
Dihydropyrimidine dehydrogenase (DPD) deficiency. Pregnancy.
EFUDEX CREAM Warnings/Precautions:
Do not apply into eyes, nose, or mouth. Avoid mucous membranes, occlusion, ulcerated/inflamed skin, exposure to UV light. Wash hands after application if fingers were used. Advise patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended.
See Also:
EFUDEX CREAM Classification:
Antimetabolite.
Adverse Reactions:
Burning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, ulceration; leukocytosis.
Generic Drug Availability:
YES
How Supplied:
Soln (w. drop dispenser)—10mL, 25mL; Crm—40g
