Migraine and headache:

Indications for: EXCEDRIN MIGRAINE


Adult Dosage:

≥18yrs: 2 caplets with a glass of water; max 2 caplets/24hrs.

Children Dosage:

<18yrs: consult physician.

EXCEDRIN MIGRAINE Contraindications:

NSAID allergy. Varicella, vaccinia in children and teenagers.

EXCEDRIN MIGRAINE Warnings/Precautions:

Reye's syndrome. Persistent or unresponsive headache. Hypertension. Cardiovascular disease. Asthma. Peptic ulcer. GI bleeding disorders. Liver cirrhosis. Hepatic or renal impairment. Discontinue if signs/symptoms of GI bleed, migraine is not relieved or worsens after first dose, tinnitus, loss of hearing, new or unexpected symptoms develop, or severe skin reactions (eg, skin reddening, blisters, rash) occur. Headaches may worsen if used for ≥10 days per month. Elderly (≥60yrs). Pregnancy (esp. during ≥20 weeks): not recommended. Nursing mothers.


Analgesic + salicylate.


May potentiate anticoagulants, hypoglycemics, methotrexate. May antagonize uricosurics. Increased risk of liver toxicity and/or GI bleed with ≥3 alcoholic drinks/day or concomitant other drugs containing acetaminophen, NSAIDs. Caution with diuretics, corticosteroids.

Adverse Reactions:

GI upset/bleed, prolonged bleeding time, urticaria, anaphylaxis; overdosage: salicylism, hepatoxicity.

How Supplied:

Caplets—24, 100, 200