Angina:
Indications for: KATERZIA
Vasospastic and chronic stable angina. To reduce the risk of hospitalization for angina and to reduce the risk of a coronary revascularization procedure in recently documented coronary artery disease (CAD) and without heart failure or an ejection fraction <40%.
Adult Dosage:
5–10mg once daily. Elderly or hepatic insufficiency: usually 5mg once daily.
Children Dosage:
Not established.
KATERZIA Warnings/Precautions:
Severe obstructive coronary disease. Severe aortic stenosis. CHF. Hepatic dysfunction. Pregnancy. Nursing mothers.
KATERZIA Classification:
Calcium channel blocker (CCB) (dihydropyridine).
KATERZIA Interactions:
May be potentiated by CYP3A inhibitors; monitor and may need to adjust dose. Concomitant CYP3A inducers; monitor BP. Concomitant simvastatin: limit simvastatin dose to 20mg/day. May potentiate cyclosporine or tacrolimus; monitor levels and adjust dose.
Adverse Reactions:
Edema, fatigue, palpitations, dizziness, nausea, flushing, abdominal pain, somnolence.
Generic Drug Availability:
NO
How Supplied:
Susp—150mL
Hypertension:
Indications for: KATERZIA
Hypertension.
Adult Dosage:
Initially 5mg once daily. Adjust at 7–14 day intervals; usual max 10mg once daily. Small, fragile, elderly, hepatic insufficiency, patients on other antihypertensives: initially 2.5mg once daily.
Children Dosage:
<6yrs: not established. 6–17yrs: 2.5–5mg once daily.
KATERZIA Warnings/Precautions:
Severe obstructive coronary disease. Severe aortic stenosis. CHF. Hepatic dysfunction. Pregnancy. Nursing mothers.
KATERZIA Classification:
Calcium channel blocker (CCB) (dihydropyridine).
KATERZIA Interactions:
May be potentiated by CYP3A inhibitors; monitor and may need to adjust dose. Concomitant CYP3A inducers; monitor BP. Concomitant simvastatin: limit simvastatin dose to 20mg/day. May potentiate cyclosporine or tacrolimus; monitor levels and adjust dose.
Adverse Reactions:
Edema, fatigue, palpitations, dizziness, nausea, flushing, abdominal pain, somnolence.
Generic Drug Availability:
NO
How Supplied:
Susp—150mL
