Miscellaneous urogenital disorders:
Indications for: KORSUVA
Moderate to severe pruritus associated with chronic kidney disease (CKD) in adults undergoing hemodialysis (HD).
Limitations of Use:
Not recommended for patients on peritoneal dialysis.
Adult Dosage:
Give 0.5mcg/kg by IV bolus inj into the venous line of dialysis circuit at the end of each HD treatment. Administer within 60mins after completion of the syringe prep.
Children Dosage:
Not established.
KORSUVA Warnings/Precautions:
May impair mental or physical abilities. Increased somnolence in ≥65yrs. Severe hepatic impairment: not recommended. Pregnancy. Nursing.
KORSUVA Classification:
Opioid agonist.
KORSUVA Interactions:
Caution with concomitant centrally-acting depressant drugs, sedating antihistamines, opioid analgesics.
Adverse Reactions:
Diarrhea, dizziness, nausea, gait disturbances, falls, hyperkalemia, headache, somnolence, mental status change.
Generic Drug Availability:
NO
How Supplied:
Single-dose vial—1, 12