Diarrhea:
Indications for: LOMOTIL
Adjunct therapy in the management of diarrhea.
Adult Dosage:
≥13yrs: 2 tabs 4 times daily until diarrhea is controlled; max 20mg/day. Maintenance: 2 tabs daily. Discontinue if no improvement within 10 days after treatment with max dose.
Children Dosage:
<13yrs: not established.
LOMOTIL Contraindications:
Age <6yrs (risks of respiratory and/or CNS depression). Diarrhea associated with pseudomembranous enterocolitis or other enterotoxin-producing bacteria due to risk of GI complications (including sepsis). Obstructive jaundice.
LOMOTIL Warnings/Precautions:
Dehydration. Electrolyte imbalance. Acute ulcerative colitis; discontinue if toxic megacolon occurs. Hepatic or renal impairment. Drug abusers. Pregnancy. Nursing mothers.
LOMOTIL Classification:
Opioid + anticholinergic.
LOMOTIL Interactions:
Avoid alcohol. Concomitant MAOIs may cause hypertensive crisis; avoid use. Potentiates sedation with alcohol or other CNS depressants (eg, barbiturates, benzodiazepines, sedatives/hypnotics, anxiolytics, tranquilizers, general anesthetics, antipsychotics, opioids, buspirone, antihistamines, muscle relaxants); monitor closely. May delay elimination of other drugs metabolized by CPY450.
Adverse Reactions:
Nausea, vomiting, abdominal discomfort, paralytic ileus, toxic megacolon, dizziness, drowsiness, headache, euphoria, tachycardia, numbness of extremities, pruritus, urticaria, angioneurotic edema, anticholinergic effects; respiratory depression (overdosage), atropinism (esp. in pediatrics with Down's syndrome).
How Supplied:
Tabs—100
