Arthritis/rheumatic disorders:

Indications for: MONOVISC

Treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy or simple analgesics (eg, acetaminophen).

Adult Dosage:

Remove synovial fluid or effusion before inj. Give as a single intra-articular inj. 4mL in one knee only. If bilateral treatment: use one syringe in each knee.

Children Dosage:

≤21yrs: not established.

MONOVISC Contraindications:

Gram (+) bacterial protein allergy. Infections or skin diseases in area of inj site/joint. Systemic bleeding disorders.

MONOVISC Warnings/Precautions:

Avoid strenuous or prolonged weight-bearing activities within 48hrs following inj. Pregnancy, nursing mothers: not established.

MONOVISC Classification:

Hyaluronan.

MONOVISC Interactions:

Avoid use of disinfectants containing quaternary ammonium salts; hyaluronan can precipitate in their presence.

Adverse Reactions:

Arthralgia, joint swelling, inj site pain.

Generic Drug Availability:

NO

How Supplied:

Single-use syringe (4mL)—1